Discovery of novel anelloviruses in small mammals expands the host range and diversity of the Anelloviridae

William Marciel de Souza, Marcílio Jorge Fumagalli, Jansen de Araujo, Gilberto Sabino-Santos, Felipe Gonçalves Motta Maia, Marilia Farignoli Romeiro, Sejal Modha, Marcello Schiavo Nardi, Luzia Helena Queiroz, Edison Luiz Durigon, Márcio Roberto Teixeira Nunes, Pablo Ramiro Murcia, Luiz Tadeu Moraes Figueiredo

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

The Anelloviridae comprises single-stranded DNA viruses currently grouped in sixty-eight species classified in twelve genera. They have been found in many vertebrate hosts including primates. In this study, we describe the application of the high-throughput sequencing to examine the frequency and diversity of anelloviruses in rodents, bats and opossums captured in São Paulo State, Brazil. We report a total of twenty-six anelloviruses with sixteen nearly complete genomes and ten partial genomes, which include eleven potential novel species identified in rodents (Cricetidae), bats (Molossidae and Phyllostomidae), and opossums (Didelphidae). We also propose the inclusion of two potential new genera within the Anelloviridae family, provisionally named Omegatorquevirus and Sigmatorquevirus, including six and three novel species of anelloviruses, respectively. In summary, this study expands the diversity and the host range of the known anelloviruses.

Original languageEnglish
Pages (from-to)9-17
Number of pages9
JournalVirology
Volume514
DOIs
StatePublished - Jan 15 2018

Bibliographical note

Publisher Copyright:
© 2017 Elsevier Inc.

Keywords

  • Anelloviridae
  • Anellovirus
  • Bat-borne virus
  • Rodent-borne virus
  • Virome, and ssDNA viruses

ASJC Scopus subject areas

  • Virology

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