Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase

Lei Zhang; Xiaojie Chen; Jun Liu; Qingzhang Zhu; Ying Leng; Xiaomin Luo; Hualiang Jiang; Hong Liu

doi:10.1016/j.ejmech.2012.06.020

Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase

Lei Zhang
, Xiaojie Chen
, Jun Liu
, Qingzhang Zhu
, Ying Leng
, Xiaomin Luo
, Hualiang Jiang
, Hong Liu

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	624-639
Number of pages	16
Journal	European Journal of Medicinal Chemistry
Volume	58
DOIs	https://doi.org/10.1016/j.ejmech.2012.06.020
State	Published - Dec 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Dual-target-directed
Glucokinase activators
Glycogen phosphorylase inhibitors
Hybrid
Type 2 diabetes

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10.1016/j.ejmech.2012.06.020

Cite this

@article{ee0c88911f0b4e03a887c082419b2975,

title = "Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase",

keywords = "Dual-target-directed, Glucokinase activators, Glycogen phosphorylase inhibitors, Hybrid, Type 2 diabetes",

author = "Lei Zhang and Xiaojie Chen and Jun Liu and Qingzhang Zhu and Ying Leng and Xiaomin Luo and Hualiang Jiang and Hong Liu",

year = "2012",

month = dec,

doi = "10.1016/j.ejmech.2012.06.020",

language = "English",

volume = "58",

pages = "624--639",

}

TY - JOUR

T1 - Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase

AU - Zhang, Lei

AU - Chen, Xiaojie

AU - Liu, Jun

AU - Zhu, Qingzhang

AU - Leng, Ying

AU - Luo, Xiaomin

AU - Jiang, Hualiang

AU - Liu, Hong

PY - 2012/12

Y1 - 2012/12

KW - Dual-target-directed

KW - Glucokinase activators

KW - Glycogen phosphorylase inhibitors

KW - Hybrid

KW - Type 2 diabetes

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=elsevierpure&SrcAuth=WosAPI&KeyUT=WOS:000312745100064&DestLinkType=FullRecord&DestApp=WOS_CPL

U2 - 10.1016/j.ejmech.2012.06.020

DO - 10.1016/j.ejmech.2012.06.020

M3 - Article

C2 - 23178962

SN - 0223-5234

VL - 58

SP - 624

EP - 639

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

ER -

Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase

UN SDGs

Keywords

Access to Document

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