Disentangling cognitive processes in externalizing psychopathology using drift diffusion modeling: Antagonism, but not disinhibition, is associated with poor cognitive control

Nathan T. Hall, Alison M. Schreiber, Timothy A. Allen, Michael N. Hallquist

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Although externalizing psychopathology has been linked to deficits in cognitive control, the cognitive processes underlying this association are unclear. Here, we provide a theoretical account of how research on cognitive processes can help to integrate and distinguish personality and psychopathology. We then apply this account to connect the two major subcomponents of externalizing, Antagonism and Disinhibition, with specific control processes using a battery of inhibitory control tasks and corresponding computational modeling. Participants (final N = 104) completed the flanker, go/no-go, and recent probes tasks, as well as normal and maladaptive personality inventories and measures of psychological distress. We fit participants' task behavior using a hierarchical drift diffusion model (DDM) to decompose their responses into specific cognitive processes. Using multilevel structural equation models, we found that Antagonism was associated with faster RTs on the flanker task and lower accuracy on flanker and go/no-go tasks. These results were complemented by DDM parameter associations: Antagonism was linked to decreased threshold and drift rate parameter estimates in the flanker task and a decreased drift rate on no-go trials. Altogether, our findings indicate that Antagonism is associated with specific impairments in fast (sub-second) inhibitory control processes involved in withholding prepared/prepotent responses and filtering distracting information. Disinhibition and momentary distress, however, were not associated with task performance.

Original languageEnglish
Pages (from-to)970-985
Number of pages16
JournalJournal of Personality
Volume89
Issue number5
DOIs
StatePublished - Oct 2021

Bibliographical note

Publisher Copyright:
© 2021 Wiley Periodicals LLC.

Funding

This work was funded by the National Institute of Mental Health (R01 MH119399 to MNH; T32‐MH016804 and K01‐MH123915 to TAA). The funding agency had no role in the design and conduct of the study; the collection, management, analysis, and interpretation of the data; the preparation, review, and approval of the manuscript; or the decision to submit the manuscript for publication.

FundersFunder number
National Institute of Mental HealthR01 MH119399, K01‐MH123915, T32MH016804
National Institute of Mental Health

    Keywords

    • antagonism
    • cognitive control
    • drift diffusion model
    • externalizing
    • inhibition

    ASJC Scopus subject areas

    • Social Psychology

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