Dissolution of bioactive glasses: The effects of crystallinity coupled with stress

John A. Nychka, Sherri L.R. Mazur, Satadru Kashyap, Ding Li, Fuqian Yang

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Fixing the chemical composition of bioactive ceramic glass does not dictate biological response. Processing history can alter the microstructure, phase composition, degree of crystallinity, and residual stress-all of which can contribute to mechanical performance and bioactive response. This paper discusses effects of thermal and mechanical processing performed on bioactive glass 45S5 with regard to the micro-structural changes that occur during in vitro immersion, and how such changes can be related to bioactivity with respect to implant materials. The underlying theme is the relationship between mechanical properties, stress, microstructure, and bioactivity, and how to achieve optimization.

Original languageEnglish
Pages (from-to)45-51
Number of pages7
Issue number9
StatePublished - Sep 2009

Bibliographical note

Funding Information:
Financial support is greatly acknowledged from the Natural Sciences and Engineering Research Council of Canada (NSERC) under Discovery Grant #9033327 and NSERC Undergraduate Student Research Award #167330.

ASJC Scopus subject areas

  • General Materials Science
  • General Engineering


Dive into the research topics of 'Dissolution of bioactive glasses: The effects of crystallinity coupled with stress'. Together they form a unique fingerprint.

Cite this