DNA "fingerprinting" reveals high levels of inbreeding in colonies of the eusocial naked mole-rat

Hudson K. Reeve, David F. Westneat, William A. Noon, Paul W. Sherman, Charles F. Aquadro

Research output: Contribution to journalArticlepeer-review

278 Scopus citations

Abstract

Using the technique of DNA fingerprinting, we investigated the genetic structure within and among four wild-caught colonies (n = 50 individuals) of a eusocial mammal, the naked mole-rat (Heterocephalus glaber; Rodentia: Bathyergidae). We found that DNA fingerprints of colonymates were strikingly similar and that between colonies they were much more alike than fingerprints of non-kin in other free-living vertebrates. Extreme genetic similarity within colonies is due to close genetic relationship (mean relatedness estimate ± SE, r̄ = 0.81 ± 0.10), which apparently results from consanguineous mating. The inbreeding coefficient (F = 0.45 ± 0.18) is the highest yet recorded among wild mammals. The genetic structure of naked mole-rat colonies lends support to kin selection and ecological constraints models for the evolution of cooperative breeding and eusociality.

Original languageEnglish
Pages (from-to)2496-2500
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume87
Issue number7
DOIs
StatePublished - Apr 1990

Keywords

  • Cooperative breeding
  • Eusociality
  • Hypervariable minisatellite DNA
  • Kin selection

ASJC Scopus subject areas

  • General

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