Dosimetric evaluation of parallel opposed spatially fractionated radiation therapy of deep-seated bulky tumors

Ali S. Meigooni; Michael Gnaster; Kai Dou; Ellis L. Johnson; Navid J. Meigooni; Mahesh Kudrimoti

doi:10.1118/1.2431423

Dosimetric evaluation of parallel opposed spatially fractionated radiation therapy of deep-seated bulky tumors

Ali S. Meigooni, Michael Gnaster, Kai Dou, Ellis L. Johnson, Navid J. Meigooni, Mahesh Kudrimoti

Radiation Medicine

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Application of a single fraction of parallel opposed GRID beams as a means of increasing the efficiency of radiation delivery to deep-seated tumors has been investigated. This evaluation was performed by measurement of dosimetric characteristics of the GRID radiation field in parallel opposed and single beam geometry. The limitations of the parallel opposed technique in terms of field size and tumor thickness have been evaluated for the conditions of acceptable spatial modulation. The results of this investigation have demonstrated an increase in therapeutic advantage for the parallel opposed technique over the single beam method when treating a deep seated tumor.

Original language	English
Pages (from-to)	599-603
Number of pages	5
Journal	Medical Physics
Volume	34
Issue number	2
DOIs	https://doi.org/10.1118/1.2431423
State	Published - 2007

Keywords

Dosimetry
GRID radiation
Parallel opposed
SFR

ASJC Scopus subject areas

Biophysics
Radiology Nuclear Medicine and imaging

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10.1118/1.2431423

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abstract = "Application of a single fraction of parallel opposed GRID beams as a means of increasing the efficiency of radiation delivery to deep-seated tumors has been investigated. This evaluation was performed by measurement of dosimetric characteristics of the GRID radiation field in parallel opposed and single beam geometry. The limitations of the parallel opposed technique in terms of field size and tumor thickness have been evaluated for the conditions of acceptable spatial modulation. The results of this investigation have demonstrated an increase in therapeutic advantage for the parallel opposed technique over the single beam method when treating a deep seated tumor.",

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AU - Dou, Kai

AU - Johnson, Ellis L.

AU - Meigooni, Navid J.

AU - Kudrimoti, Mahesh

PY - 2007

Y1 - 2007

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AB - Application of a single fraction of parallel opposed GRID beams as a means of increasing the efficiency of radiation delivery to deep-seated tumors has been investigated. This evaluation was performed by measurement of dosimetric characteristics of the GRID radiation field in parallel opposed and single beam geometry. The limitations of the parallel opposed technique in terms of field size and tumor thickness have been evaluated for the conditions of acceptable spatial modulation. The results of this investigation have demonstrated an increase in therapeutic advantage for the parallel opposed technique over the single beam method when treating a deep seated tumor.

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KW - GRID radiation

KW - Parallel opposed

KW - SFR

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Dosimetric evaluation of parallel opposed spatially fractionated radiation therapy of deep-seated bulky tumors

Abstract

Keywords

ASJC Scopus subject areas

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