Effect of amitraz and xylazine on some physiological variables of horses

A. Queiroz-Neto, A. B. Carregaro, G. Zamur, J. D. Harkins, T. Tobin, M. I. Mataqueiro, S. C. Gonçalves

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The effect of the intravenous injection of amitraz (0.1 mg/kg) to horses on cardiac activity, respiratory rate, intestinal motor activity, rectal temperature, sweating and masticating was evaluated and compared to the effect of intravenous administration of xylazine (1mg/kg, iv) on heart rate, respiratory rate and intestinal activity. Amitraz caused a significant decrease in heart activity, respiratory rate and intestinal movements, but these effects were not as pronounced as those caused by xylazine. Amitraz also caused a significant relaxation of the rectal smooth muscle, and an apparent increase in sweating and in the frequency of horses found masticating hay. Rectal temperature was not influenced by amitraz. The results indicated that amitraz, at the dose used, did not cause severe side effects in horses.

Original languageEnglish
Pages (from-to)27-32
Number of pages6
JournalArquivo Brasileiro de Medicina Veterinaria e Zootecnia
Issue number1
StatePublished - Feb 2000


  • Amitraz
  • Cardiac activity
  • Horse
  • Intestinal activity
  • Respiratory activity
  • Xylazine

ASJC Scopus subject areas

  • General Veterinary


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