TY - JOUR
T1 - Effects of acute and chronic murine norovirus infections on immune responses and recovery from friend retrovirus infection
AU - Ammann, Christoph G.
AU - Messer, Ronald J.
AU - Varvel, Kimberly
AU - DeBuysscher, Blair L.
AU - LaCasse, Rachel A.
AU - Pinto, Amelia K.
AU - Hasenkrug, Kim J.
PY - 2009/12
Y1 - 2009/12
N2 - Murine norovirus (MNV) is a highly infectious but generally nonpathogenic agent that is commonly found in research mouse colonies in both North America and Europe. In the present study, the effects of acute and chronic infections with MNV on immune responses and recovery from concurrent Friend virus (FV) infections were investigated. No significant differences in T-cell or NK-cell responses, FV-neutralizing antibody responses, or long-term recovery from FV infection were observed. We conclude that concurrent MNV infections had no major impacts on FV infections.
AB - Murine norovirus (MNV) is a highly infectious but generally nonpathogenic agent that is commonly found in research mouse colonies in both North America and Europe. In the present study, the effects of acute and chronic infections with MNV on immune responses and recovery from concurrent Friend virus (FV) infections were investigated. No significant differences in T-cell or NK-cell responses, FV-neutralizing antibody responses, or long-term recovery from FV infection were observed. We conclude that concurrent MNV infections had no major impacts on FV infections.
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U2 - 10.1128/JVI.01445-09
DO - 10.1128/JVI.01445-09
M3 - Article
C2 - 19812147
AN - SCOPUS:72849110339
SN - 0022-538X
VL - 83
SP - 13037
EP - 13041
JO - Journal of Virology
JF - Journal of Virology
IS - 24
ER -