Effects of d-amphetamine on aggressive responding of normal male subjects

Don R. Cherek; Joel L. Steinberg; Thomas H. Kelly; Dean Robinson

doi:10.1016/0165-1781(87)90030-8

Effects of d-amphetamine on aggressive responding of normal male subjects

Don R. Cherek, Joel L. Steinberg, Thomas H. Kelly, Dean Robinson

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Male research subjects were administered placebo and three doses of d-amphetamine (5, 10, and 20 mg/70 kg of body weight) under double-blind conditions in a laboratory situation that provided both aggressive and nonaggressive response options. The nonaggressive response was button pressing maintained by the presentation of points which were exchanged for money. The aggressive response was button pressing on a separate manipulandum which ostensibly subtracted points from a fictitious person. Aggressive responding was initially established by subtracting points from the research subjects, which was attributed to the other person. d-Amphetamine increased nonaggressive responding, while aggressive responding was generally decreased.

Original language	English
Pages (from-to)	257-265
Number of pages	9
Journal	Psychiatry Research
Volume	21
Issue number	3
DOIs	https://doi.org/10.1016/0165-1781(87)90030-8
State	Published - Jul 1987

Bibliographical note

Funding Information:
Acknowledgments. The authors thank Steve Mathews for his expert technical assistance. This research was supported by a grant from the National Institute on Drug Abuse (NIDA), DA-03 166. Thomas H. Kelly was supported by a NIDA postdoctoral fellowship, DA-05277.

Keywords

Aggressive behavior
d-amphetamine
human
laboratory
normal

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0165-1781(87)90030-8

Cite this

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abstract = "Male research subjects were administered placebo and three doses of d-amphetamine (5, 10, and 20 mg/70 kg of body weight) under double-blind conditions in a laboratory situation that provided both aggressive and nonaggressive response options. The nonaggressive response was button pressing maintained by the presentation of points which were exchanged for money. The aggressive response was button pressing on a separate manipulandum which ostensibly subtracted points from a fictitious person. Aggressive responding was initially established by subtracting points from the research subjects, which was attributed to the other person. d-Amphetamine increased nonaggressive responding, while aggressive responding was generally decreased.",

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AU - Kelly, Thomas H.

AU - Robinson, Dean

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Effects of d-amphetamine on aggressive responding of normal male subjects

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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