Effects of multidisciplinary case management in patients with chronic renal insufficiency

Lisa E. Harris, Friedrich C. Luft, David W. Rudy, Joseph G. Kesterson, William M. Tierney

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PURPOSE: Though case management has been recommended to improve the outcomes of patients with costly or morbid conditions, it has seldom been studied in controlled trials. We performed a randomized, controlled clinical trial of an intensive, multidisciplinary case management program for patients with chronic renal insufficiency and followed patients for 5 years. PATIENTS AND METHODS: We enrolled 437 primary-care patients (73% of those eligible) with chronic renal insufficiency (estimated creatinine clearance consistently <50 mL/min with the last serum Creatinine level > 1.4 mg/dL) who were attending an urban academic general internal medicine practice. The intensive case management, administered during the first 2 years after enrollment, consisted of mandatory repeated consultations in a nephrology case management clinic staffed by two nephrologists, a renal nurse, a renal dietitian, and a social worker. Control patients received usual care. Primary outcome measurements included serum creatinine level, estimated creatinine clearance, health services use, and mortality in the 5 years after enrollment. Secondary measures included use of renal sparing and potentially nephrotoxic drugs. RESULTS: There were no differences in renal function, health services use, or mortality in the first, second, or third through fifth years after enrollment. There were significantly more outpatient visits among intervention patients, mainly because of the added visits to the nephrology case management clinic. There were also no significant differences in the use of renal sparing or selected potentially nephrotoxic drugs. The annual direct costs of the intervention were $89,355 ($484 per intervention patient). CONCLUSION: This intensive, multidisciplinary case-management intervention had no effect on the outcomes of care among primary-care patients with established chronic renal in, sufficiency. Such expensive and intrusive interventions, despite representing state-of-the-art care, should be tested prospectively before being widely introduced into practice.

Original languageEnglish
Pages (from-to)464-471
Number of pages8
JournalAmerican Journal of Medicine
Issue number6
StatePublished - Dec 1998

Bibliographical note

Funding Information:
Supported in part by grants from The Indianapolis Health Foundation (FCL), The Indianapolis Foundation (LEH, WMT), The Picker-Commonwealth Program for Patient-Centered Care (LEH), and The Agency for Health Care Policy and Research (HS04996, HS05626, HS07632, HS07719, HS07763, and HS09083) (WMT).

Copyright 2007 Elsevier B.V., All rights reserved.

ASJC Scopus subject areas

  • Medicine (all)


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