Effects of Pharmacological Levels of Zinc as Zinc Oxide on Fecal Zinc and Mineral Excretion in Weanling Pigs

T. A. Meyer, M. D. Lindemann, G. L. Cromwell, H. J. Monegue, N. Inocencio

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Eighteen weanling crossbred barrows (7.3 kg; 22 d of age) were used in a randomized complete block design to evaluate the effect of supplemental Zn from ZnO on fecal excretion of Zn and other minerals. Pigs were blocked by BW and penned (two pigs per crate) in stainless steel metabolism crates. Dietary treatments were 0, 2,000, or 3,000 ppm supplemental Zn from ZnO. Growth performance and feed intake were measured weekly for a total of 21 d. Excretion of minerals was measured by total fecal collection with indigo carmine marking the beginning and end of each weekly period. No differences (P > 0.05) occurred in ADG, ADFI, and feed/gain (F/G) among treatments. Increasing dietary Zn increased (linear, P < 0.01) Zn intake, absolute absorption of Zn, and absolute fecal excretion of Zn. Increasing dietary Zn also increased absolute excretion of Fe, Cu, and Mn and decreased apparent absorption of P, Fe, and Cu (linear, P < 0.05) for the entire period. Fecal N increased, and N digestibility decreased, with increasing dietary Zn (linear, P < 0.05). Increasing dietary Zn increased fecal DM (quadratic, P < 0.05) and decreased DM digestibility (quadratic, P < 0.05). Increasing dietary Zn also increased liver Zn (quadratic, P < 0.01) and decreased (linear, P < 0.05) liver Cu and Mn. Overall, pharmacological levels of Zn reduced Zn and other mineral apparent absorption and increased fecal mineral excretion.

Original languageEnglish
Pages (from-to)162-168
Number of pages7
JournalProfessional Animal Scientist
Issue number2
StatePublished - Jun 1 2002

Bibliographical note

Publisher Copyright:
© 2002 American Registry of Professional Animal Scientists


  • Feces
  • Liver
  • Pigs
  • Quality Audits
  • Zinc

ASJC Scopus subject areas

  • Food Science
  • Animal Science and Zoology


Dive into the research topics of 'Effects of Pharmacological Levels of Zinc as Zinc Oxide on Fecal Zinc and Mineral Excretion in Weanling Pigs'. Together they form a unique fingerprint.

Cite this