TY - JOUR
T1 - Efficacy of the de novo-derived antimicrobial peptide WLBU2 against oral bacteria
AU - Novak, Karen F.
AU - Diamond, William J.
AU - Kirakodu, Sreenatha
AU - Peyyala, Rebecca
AU - Anderson, Kimberly W.
AU - Montelaro, Ronald C.
AU - Mietzner, Timothy A.
PY - 2007/5
Y1 - 2007/5
N2 - The efficacy of a novel synthetic antimicrobial peptide (WLBU2) was evaluated against three oral microorganisms (grown planktonically): Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis. WLBU2 killed all three species, with F. nucleatum being the most susceptible. WLBU2 also reduced the bacterial burden of S. gordonii and F. nucleatum biofilms.
AB - The efficacy of a novel synthetic antimicrobial peptide (WLBU2) was evaluated against three oral microorganisms (grown planktonically): Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis. WLBU2 killed all three species, with F. nucleatum being the most susceptible. WLBU2 also reduced the bacterial burden of S. gordonii and F. nucleatum biofilms.
UR - http://www.scopus.com/inward/record.url?scp=34248386794&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34248386794&partnerID=8YFLogxK
U2 - 10.1128/AAC.00924-06
DO - 10.1128/AAC.00924-06
M3 - Article
C2 - 17325219
AN - SCOPUS:34248386794
SN - 0066-4804
VL - 51
SP - 1837
EP - 1839
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 5
ER -
