Electrochemical Treatment of Glassy Carbon for Label-Free Detection of DNA Bases and Neurotransmitters

Yan Zhang, Doo Young Kim

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Electrochemically reduced glassy carbon (r-GC) showed a superior electrochemical sensing performance, compared to oxidized GC (ox-GC) and untreated GC for the oxidation of 4 DNA bases and neurotransmitters (epinephrine, norepinephrine and serotonin). r-GC exhibited not only the largest current intensities of all redox biomolecules, but also displayed an excellent selectivity in detecting coexisting redox biomolecules. The enhanced performance of r-GC was attributed to the improved surface cleanliness of electrode and its catalytic surface functional groups. The results presented herein imply that simple electrochemical treatments are a viable method to produce sensitive and selective electrodes for label-free biosensing.

Original languageEnglish
Pages (from-to)2581-2587
Number of pages7
Issue number11
StatePublished - Nov 1 2015

Bibliographical note

Publisher Copyright:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


  • DNA bases
  • Electrochemical treatment
  • Glassy carbon
  • Neurotransmitters

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry


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