Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes

Claudio W. Pikielny, Brian C. Rymond, Michael Rosbash

Research output: Contribution to journalArticlepeer-review

142 Scopus citations

Abstract

Three splicing complexes formed with a yeast pre-messenger RNA during in vitro splicing can be resolved by non-denaturing gel electrophoresis after incubation in the presence of non-specific competitor RNA. The time course of the appearance of these complexes and their composition suggest that they represent an ordered pathway of splicing complex assembly.

Original languageEnglish
Pages (from-to)341-345
Number of pages5
JournalNature
Volume324
Issue number6095
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • General

Fingerprint

Dive into the research topics of 'Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes'. Together they form a unique fingerprint.

Cite this