TY - JOUR
T1 - Emerging concepts in alcohol, infection & immunity
T2 - A summary of the 2023 alcohol and immunology research interest group (AIRIG) meeting
AU - Rutt, Lauren N.
AU - Liu, Mengfei
AU - Melamed, Esther
AU - Twardy, Shannon
AU - Sturgill, Jamie L.
AU - Brenner, Lisa A.
AU - Hardesty, Josiah
AU - Weinman, Steven A.
AU - Tschann, Madison M.
AU - Travers, Jared
AU - Welsh, David A.
AU - Chichetto, Natalie
AU - Crotty, Kathryn M.
AU - Mackowiak, Bryan
AU - Yeligar, Samantha M.
AU - Wyatt, Todd A.
AU - McMahan, Rachel H.
AU - Choudry, Mashkoor A.
AU - Kovacs, Elizabeth J.
AU - McCullough, Rebecca L.
N1 - Publisher Copyright:
© 2024 Elsevier Inc.
PY - 2024/8
Y1 - 2024/8
N2 - On December 8th 2023, the annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at the University of Colorado Anschutz Medical Campus in Aurora, Colorado. The 2023 meeting focused broadly on how acute and chronic alcohol exposure leads to immune dysregulation, and how this contributes to damage in multiple tissues and organs. These include impaired lung immunity, intestinal dysfunction, autoimmunity, the gut-Central Nervous System (CNS) axis, and end-organ damage. In addition, diverse areas of alcohol research covered multiple pathways behind alcohol-induced cellular dysfunction, including inflammasome activation, changes in miRNA expression, mitochondrial metabolism, gene regulation, and transcriptomics. Finally, the work presented at this meeting highlighted novel biomarkers and therapeutic interventions for patients suffering from alcohol-induced organ damage.
AB - On December 8th 2023, the annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at the University of Colorado Anschutz Medical Campus in Aurora, Colorado. The 2023 meeting focused broadly on how acute and chronic alcohol exposure leads to immune dysregulation, and how this contributes to damage in multiple tissues and organs. These include impaired lung immunity, intestinal dysfunction, autoimmunity, the gut-Central Nervous System (CNS) axis, and end-organ damage. In addition, diverse areas of alcohol research covered multiple pathways behind alcohol-induced cellular dysfunction, including inflammasome activation, changes in miRNA expression, mitochondrial metabolism, gene regulation, and transcriptomics. Finally, the work presented at this meeting highlighted novel biomarkers and therapeutic interventions for patients suffering from alcohol-induced organ damage.
KW - Alcohol
KW - Complosome
KW - Immunoglobulins
KW - Immunometabolism
KW - Infection
KW - Lung
UR - http://www.scopus.com/inward/record.url?scp=85190771975&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85190771975&partnerID=8YFLogxK
U2 - 10.1016/j.alcohol.2024.04.002
DO - 10.1016/j.alcohol.2024.04.002
M3 - Article
C2 - 38582261
AN - SCOPUS:85190771975
SN - 0741-8329
VL - 118
SP - 9
EP - 16
JO - Alcohol
JF - Alcohol
ER -