Endoscopic Pancreatic Function Test for the Functional Diagnosis of Chronic Pancreatitis: Indications and Practical Protocol

Luis F. Lara, Darwin L. Conwell

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Evaluation of the pancreas improved with the advent of endoscopic ultrasound (EUS), and more recently with secretin-stimulated magnetic resonance cholangiopancreatography (sMRCP), which may even provide information about the function of the pancreas. However, diagnosing early chronic pancreatitis (CP) remains a challenge. In this chapter, a brief history of pancreatic function is followed by a review of pancreas function tests. The evolution to endoscopic-based secretin-stimulated tests is then described, and current indications for pancreatic function testing are presented. Updated protocols are described with a discussion of their current role in the evaluation of pancreatic disease. Endoscopic aspiration of pancreatic juice following secretin administration is an appropriate test of pancreatic exocrine function. It is approved by the Food and Drug Administration of the United States.

Original languageEnglish
Title of host publicationClinical Pancreatology for Practising Gastroenterologists and Surgeons
Subtitle of host publicationSecond Edition
Pages243-249
Number of pages7
ISBN (Electronic)9781119570097
DOIs
StatePublished - Jan 1 2021

Bibliographical note

Publisher Copyright:
© 2021 John Wiley and Sons Ltd.

Keywords

  • chronic pancreatitis
  • endoscopic aspiration
  • functional diagnosis
  • pancreatic function test
  • secretin-stimulated magnetic resonance cholangiopancreatography

ASJC Scopus subject areas

  • General Medicine

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