Equid Herpesvirus-Associated Myeloencephalopathy

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


Equid herpesvirus-associated myeloencephalopathy (EHM) is an infrequent but serious outcome of common equid herpesvirus type 1 (EHV-1) infection in horses. Basic information on the virus that is associated with EHM is deemed necessary as it aids our understanding of virus-specific strategy and virus-host interaction. Equine herpesvirus myeloencephalopathy is caused by a multifocal, stroke-like disease in the vasculature of the central nervous system (CNS), mainly in the spinal cord. Clinical signs typical of EHM are those attributed to spinal cord damage. A diagnosis of EHM is easy to establish when several horses are febrile, some of them with clinical signs of spinal cord disease. Many different therapeutic options such as dimethyl sulfoxide (DMSO), heparin, and low-dose aspirin are used empirically to prevent secondary complications at different stages of this disease despite a lack of evidence of efficacy. Equine herpesvirus myeloencephalitis outbreak prevention requires a stringent immunization protocol.

Original languageEnglish
Title of host publicationEquine Neurology
Subtitle of host publicationSecond Edition
Number of pages10
ISBN (Electronic)9781118993712
StatePublished - Aug 3 2015

Bibliographical note

Publisher Copyright:
© 2015 John Wiley & Sons, Inc.


  • Aspirin
  • Central nervous system (CNS)
  • Dimethyl sulfoxide (DMSO)
  • Equid herpesvirus type 1 (EHV-1) infection
  • Equid herpesvirus-associated myeloencephalopathy (EHM)
  • Horses
  • Immunization protocol
  • Myeloencephalopathy
  • Spinal cord

ASJC Scopus subject areas

  • General Veterinary


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