TY - JOUR
T1 - Equine herpesvirus type 1-associated myeloencephalopathy in The Netherlands
T2 - A four-year retrospective study (1999-2003)
AU - Goehring, Lutz S.
AU - Van Winden, Steven C.
AU - Van Maanen, C.
AU - Sloet Van Oldruitenborgh-Oosterbaan, Marianne M.
PY - 2006/5
Y1 - 2006/5
N2 - Equine herpesvirus type 1(EHV-1)-associated myeloencephalopathy (EHM) is a rare disease affecting the central nervous system and, in particular, the spinal cord of horses. Epidemiologic data are limited, and usually are restricted to the description of a single outbreak. During an observational period of 4 years, we evaluated 9 outbreaks of EHM in The Netherlands. A risk factor analysis was done on the data from 6 outbreaks. Findings were: regular appearance of EHM outbreaks in The Netherlands (2-3/y); strong association of EHM with season; and risk factors, such as breed, sex, age, and fever. Female horses, aged horses, and specific breeds were at greater risk to develop severe neurologic disease. Other breeds and horses <3 years old were never observed to suffer from EHM during these outbreaks. It was concluded that breed variation, in addition to the presence of a specific EHV-1 strain, and environmental factors influence an outbreak of EHM on a premise.
AB - Equine herpesvirus type 1(EHV-1)-associated myeloencephalopathy (EHM) is a rare disease affecting the central nervous system and, in particular, the spinal cord of horses. Epidemiologic data are limited, and usually are restricted to the description of a single outbreak. During an observational period of 4 years, we evaluated 9 outbreaks of EHM in The Netherlands. A risk factor analysis was done on the data from 6 outbreaks. Findings were: regular appearance of EHM outbreaks in The Netherlands (2-3/y); strong association of EHM with season; and risk factors, such as breed, sex, age, and fever. Female horses, aged horses, and specific breeds were at greater risk to develop severe neurologic disease. Other breeds and horses <3 years old were never observed to suffer from EHM during these outbreaks. It was concluded that breed variation, in addition to the presence of a specific EHV-1 strain, and environmental factors influence an outbreak of EHM on a premise.
KW - Clustered neurologic disease
KW - Horse
KW - Risk factor
UR - http://www.scopus.com/inward/record.url?scp=33646822508&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33646822508&partnerID=8YFLogxK
U2 - 10.1892/0891-6640(2006)20[601:EHTAMI]2.0.CO;2
DO - 10.1892/0891-6640(2006)20[601:EHTAMI]2.0.CO;2
M3 - Article
C2 - 16734096
AN - SCOPUS:33646822508
SN - 0891-6640
VL - 20
SP - 601
EP - 607
JO - Journal of Veterinary Internal Medicine
JF - Journal of Veterinary Internal Medicine
IS - 3
ER -