Abstract
Horses are the third major mammalian species, along with humans and swine, long known to be subject to acute upper respiratory disease from influenza A virus infection. The viruses responsible are subtype H7N7, which is believed extinct, and H3N8, which circulates world-wide. The equine influenza lineages are clearly divergent from avian influenza lineages of the same subtypes. Their genetic evolution and potential for interspecies transmission, as well as clinical features and epidemiology, are discussed. Equine influenza is spread internationally and vaccination is central to control efforts. The current mechanism of international surveillance and virus strain recommendations for vaccines is described.
| Original language | English |
|---|---|
| Article number | a038331 |
| Journal | Cold Spring Harbor perspectives in medicine |
| Volume | 12 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2022 |
Bibliographical note
Funding Information:We thank Ms. Diane Furry (University of Kentucky) for creation of Figure 1 and Drs. Adam Rash and Debra Elton, Animal Health Trust, United Kingdom, for the generation of the phylogenetic tree presented as Figure 2. T.M.C. is supported by a project of the Kentucky Agricultural Experiment Station (KY014053). This article has been made freely available online courtesy of TAUNS Laboratories.
Funding Information:
We thank Ms. Diane Furry (University of Kentucky) for creation of Figure 1 and Drs. Adam Rash and Debra Elton, Animal Health Trust, United Kingdom, for the generation of the phylogenetic tree presented as Figure 2. T.M.C. is supported by a project of the Kentucky Agricultural Experiment Station (KY014053).
Publisher Copyright:
© 2022 Cold Spring Harbor Laboratory Press; all rights reserved.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology (all)
