Abstract
In recent years our appreciation that estradiol is truly a pleiotropic hormone has grown dramatically. We will review the findings that suggest that estrogens may exert important non-reproductive actions on the brain. These studies provide important insights into the clinical effects of estrogen replacement therapy on age- and disease-related processes in the brain. We will also discuss the multiple cellular and molecular mechanisms that may underlie estradiol's neurotrophic and neuroprotective effects.
| Original language | English |
|---|---|
| Pages (from-to) | 265-274 |
| Number of pages | 10 |
| Journal | Journal of Alzheimer's Disease |
| Volume | 1 |
| Issue number | 4-5 |
| DOIs | |
| State | Published - 1999 |
ASJC Scopus subject areas
- General Neuroscience
- Clinical Psychology
- Geriatrics and Gerontology
- Psychiatry and Mental health
