Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: A consensus report

Timothy Buie; Daniel B. Campbell; George J. Fuchs; Glenn T. Furuta; Joseph Levy; Judy Van De Water; Agnes H. Whitaker; Dan Atkins; Margaret L. Bauman; Arthur L. Beaudet; Edward G. Carr; Michael D. Gershon; Susan L. Hyman; Pipop Jirapinyo; Harumi Jyonouchi; Koorosh Kooros; Rafail Kushak; Pat Levitt; Susan E. Levy; Jeffery D. Lewis; Katherine F. Murray; Marvin R. Natowicz; Aderbal Sabra; Barry K. Wershil; Sharon C. Weston; Lonnie Zeltzer; Harland Winter

doi:10.1542/peds.2009-1878C

Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: A consensus report

Timothy Buie, Daniel B. Campbell, George J. Fuchs, Glenn T. Furuta, Joseph Levy, Judy Van De Water, Agnes H. Whitaker, Dan Atkins, Margaret L. Bauman, Arthur L. Beaudet, Edward G. Carr, Michael D. Gershon, Susan L. Hyman, Pipop Jirapinyo, Harumi Jyonouchi, Koorosh Kooros, Rafail Kushak, Pat Levitt, Susan E. Levy, Jeffery D. LewisKatherine F. Murray, Marvin R. Natowicz, Aderbal Sabra, Barry K. Wershil, Sharon C. Weston, Lonnie Zeltzer, Harland Winter

Pediatrics

Research output: Contribution to journal › Article › peer-review

578 Scopus citations

Abstract

Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs.

Original language	English
Pages (from-to)	S1-S18
Journal	Pediatrics
Volume	125
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1542/peds.2009-1878C
State	Published - Jan 2010

Keywords

Abdominal discomfort
Autism spectrum disorder
Chronic diarrhea
Constipation
Gastrointestinal
Gluten-free casein-free diet
Problem behavior

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1542/peds.2009-1878C

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Buie, T., Campbell, D. B., Fuchs, G. J., Furuta, G. T., Levy, J., Van De Water, J., Whitaker, A. H., Atkins, D., Bauman, M. L., Beaudet, A. L., Carr, E. G., Gershon, M. D., Hyman, S. L., Jirapinyo, P., Jyonouchi, H., Kooros, K., Kushak, R., Levitt, P., Levy, S. E., ... Winter, H. (2010). Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: A consensus report. Pediatrics, 125(SUPPL. 1), S1-S18. https://doi.org/10.1542/peds.2009-1878C

@article{a875c13566f6401e8802fdac4de018a1,

title = "Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: A consensus report",

abstract = "Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs.",

keywords = "Abdominal discomfort, Autism spectrum disorder, Chronic diarrhea, Constipation, Gastrointestinal, Gluten-free casein-free diet, Problem behavior",

author = "Timothy Buie and Campbell, {Daniel B.} and Fuchs, {George J.} and Furuta, {Glenn T.} and Joseph Levy and {Van De Water}, Judy and Whitaker, {Agnes H.} and Dan Atkins and Bauman, {Margaret L.} and Beaudet, {Arthur L.} and Carr, {Edward G.} and Gershon, {Michael D.} and Hyman, {Susan L.} and Pipop Jirapinyo and Harumi Jyonouchi and Koorosh Kooros and Rafail Kushak and Pat Levitt and Levy, {Susan E.} and Lewis, {Jeffery D.} and Murray, {Katherine F.} and Natowicz, {Marvin R.} and Aderbal Sabra and Wershil, {Barry K.} and Weston, {Sharon C.} and Lonnie Zeltzer and Harland Winter",

year = "2010",

month = jan,

doi = "10.1542/peds.2009-1878C",

language = "English",

volume = "125",

pages = "S1--S18",

number = "SUPPL. 1",

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Buie, T, Campbell, DB, Fuchs, GJ, Furuta, GT, Levy, J, Van De Water, J, Whitaker, AH, Atkins, D, Bauman, ML, Beaudet, AL, Carr, EG, Gershon, MD, Hyman, SL, Jirapinyo, P, Jyonouchi, H, Kooros, K, Kushak, R, Levitt, P, Levy, SE, Lewis, JD, Murray, KF, Natowicz, MR, Sabra, A, Wershil, BK, Weston, SC, Zeltzer, L & Winter, H 2010, 'Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: A consensus report', Pediatrics, vol. 125, no. SUPPL. 1, pp. S1-S18. https://doi.org/10.1542/peds.2009-1878C

TY - JOUR

T1 - Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs

T2 - A consensus report

AU - Buie, Timothy

AU - Campbell, Daniel B.

AU - Fuchs, George J.

AU - Furuta, Glenn T.

AU - Levy, Joseph

AU - Van De Water, Judy

AU - Whitaker, Agnes H.

AU - Atkins, Dan

AU - Bauman, Margaret L.

AU - Beaudet, Arthur L.

AU - Carr, Edward G.

AU - Gershon, Michael D.

AU - Hyman, Susan L.

AU - Jirapinyo, Pipop

AU - Jyonouchi, Harumi

AU - Kooros, Koorosh

AU - Kushak, Rafail

AU - Levitt, Pat

AU - Levy, Susan E.

AU - Lewis, Jeffery D.

AU - Murray, Katherine F.

AU - Natowicz, Marvin R.

AU - Sabra, Aderbal

AU - Wershil, Barry K.

AU - Weston, Sharon C.

AU - Zeltzer, Lonnie

AU - Winter, Harland

PY - 2010/1

Y1 - 2010/1

N2 - Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs.

AB - Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs.

KW - Abdominal discomfort

KW - Autism spectrum disorder

KW - Chronic diarrhea

KW - Constipation

KW - Gastrointestinal

KW - Gluten-free casein-free diet

KW - Problem behavior

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U2 - 10.1542/peds.2009-1878C

DO - 10.1542/peds.2009-1878C

M3 - Article

C2 - 20048083

AN - SCOPUS:73949128465

SN - 0031-4005

VL - 125

SP - S1-S18

JO - Pediatrics

JF - Pediatrics

IS - SUPPL. 1

ER -

Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: A consensus report

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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