Evidence for the existence of a population of arcuate neurons costoring choline acetyltransferase and tyrosine hydroxylase immunoreactivities in the male rat

B. Tinner; K. Fuxe; Ch Köhler; L. Hersh; K. Andersson; A. Jansson; M. Goldstein; L. F. Agnati

doi:10.1016/0304-3940(89)90262-0

Evidence for the existence of a population of arcuate neurons costoring choline acetyltransferase and tyrosine hydroxylase immunoreactivities in the male rat

B. Tinner, K. Fuxe, Ch Köhler, L. Hersh, K. Andersson, A. Jansson, M. Goldstein, L. F. Agnati

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

By combined immunoperoxidase and immunofluorescence histochemistry we have analyzed the distribution of choline acetyltransferase (ChAT) and tyrosine hydroxylase (TH) immunoreactive (IR) perikarya within the same sections of the mediobasal hypothalamus of the male rat. Evidence was obtained for the existence of perikarya costoring TH and ChAT immunoreactivities in both the dorsomedial and ventrolateral part of the arcuate nucleus and in the adjacent periarcuate nucleus at all rostrocaudal levels. The results strongly implicate interactions between dopamine and acetylcholine as well as acetylcholine and growth hormone releasing factor in dorsomedially and ventrolaterally located TH/ChAT costoring tuberoinfundibular neurons, respectively.

Original language	English
Pages (from-to)	44-49
Number of pages	6
Journal	Neuroscience Letters
Volume	99
Issue number	1-2
DOIs	https://doi.org/10.1016/0304-3940(89)90262-0
State	Published - Apr 24 1989

Bibliographical note

Funding Information:
This work has been supportedb y Grant 1223 from the Council of Tobacco Research,N ew York, U.S.A., a grant from the SwedishT obaccoC ompanya nd Grants 12P-08127a nd 12X-08275f rom the SwedishM edicalR esearchC ouncil.

Keywords

Choline acetyltransferase
Costorage
Dopamine
Immunohistochemistry
Rat hypothalamus
Tyrosine hydroxylase

ASJC Scopus subject areas

General Neuroscience

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10.1016/0304-3940(89)90262-0

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title = "Evidence for the existence of a population of arcuate neurons costoring choline acetyltransferase and tyrosine hydroxylase immunoreactivities in the male rat",

abstract = "By combined immunoperoxidase and immunofluorescence histochemistry we have analyzed the distribution of choline acetyltransferase (ChAT) and tyrosine hydroxylase (TH) immunoreactive (IR) perikarya within the same sections of the mediobasal hypothalamus of the male rat. Evidence was obtained for the existence of perikarya costoring TH and ChAT immunoreactivities in both the dorsomedial and ventrolateral part of the arcuate nucleus and in the adjacent periarcuate nucleus at all rostrocaudal levels. The results strongly implicate interactions between dopamine and acetylcholine as well as acetylcholine and growth hormone releasing factor in dorsomedially and ventrolaterally located TH/ChAT costoring tuberoinfundibular neurons, respectively.",

keywords = "Choline acetyltransferase, Costorage, Dopamine, Immunohistochemistry, Rat hypothalamus, Tyrosine hydroxylase",

author = "B. Tinner and K. Fuxe and Ch K{\"o}hler and L. Hersh and K. Andersson and A. Jansson and M. Goldstein and Agnati, {L. F.}",

note = "Funding Information: This work has been supportedb y Grant 1223 from the Council of Tobacco Research,N ew York, U.S.A., a grant from the SwedishT obaccoC ompanya nd Grants 12P-08127a nd 12X-08275f rom the SwedishM edicalR esearchC ouncil.",

year = "1989",

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doi = "10.1016/0304-3940(89)90262-0",

language = "English",

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T1 - Evidence for the existence of a population of arcuate neurons costoring choline acetyltransferase and tyrosine hydroxylase immunoreactivities in the male rat

AU - Tinner, B.

AU - Fuxe, K.

AU - Köhler, Ch

AU - Hersh, L.

AU - Andersson, K.

AU - Jansson, A.

AU - Goldstein, M.

AU - Agnati, L. F.

N1 - Funding Information: This work has been supportedb y Grant 1223 from the Council of Tobacco Research,N ew York, U.S.A., a grant from the SwedishT obaccoC ompanya nd Grants 12P-08127a nd 12X-08275f rom the SwedishM edicalR esearchC ouncil.

PY - 1989/4/24

Y1 - 1989/4/24

N2 - By combined immunoperoxidase and immunofluorescence histochemistry we have analyzed the distribution of choline acetyltransferase (ChAT) and tyrosine hydroxylase (TH) immunoreactive (IR) perikarya within the same sections of the mediobasal hypothalamus of the male rat. Evidence was obtained for the existence of perikarya costoring TH and ChAT immunoreactivities in both the dorsomedial and ventrolateral part of the arcuate nucleus and in the adjacent periarcuate nucleus at all rostrocaudal levels. The results strongly implicate interactions between dopamine and acetylcholine as well as acetylcholine and growth hormone releasing factor in dorsomedially and ventrolaterally located TH/ChAT costoring tuberoinfundibular neurons, respectively.

AB - By combined immunoperoxidase and immunofluorescence histochemistry we have analyzed the distribution of choline acetyltransferase (ChAT) and tyrosine hydroxylase (TH) immunoreactive (IR) perikarya within the same sections of the mediobasal hypothalamus of the male rat. Evidence was obtained for the existence of perikarya costoring TH and ChAT immunoreactivities in both the dorsomedial and ventrolateral part of the arcuate nucleus and in the adjacent periarcuate nucleus at all rostrocaudal levels. The results strongly implicate interactions between dopamine and acetylcholine as well as acetylcholine and growth hormone releasing factor in dorsomedially and ventrolaterally located TH/ChAT costoring tuberoinfundibular neurons, respectively.

KW - Choline acetyltransferase

KW - Costorage

KW - Dopamine

KW - Immunohistochemistry

KW - Rat hypothalamus

KW - Tyrosine hydroxylase

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DO - 10.1016/0304-3940(89)90262-0

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AN - SCOPUS:0024522850

SN - 0304-3940

VL - 99

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EP - 49

JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 1-2

ER -

Evidence for the existence of a population of arcuate neurons costoring choline acetyltransferase and tyrosine hydroxylase immunoreactivities in the male rat

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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