Evidence that in vitro susceptibility of CD3+ T lymphocytes to equine arteritis virus infection reflects genetic predisposition of naturally infected stallions to become carriers of the virus

Yun Young Go, Ernest Bailey, Peter J. Timoney, Kathleen M. Shuck, Udeni B.R. Balasuriya

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

We investigated the correlation between in vitro susceptibility of CD3+ T lymphocytes to equine arteritis virus (EAV) infection and establishment of persistent infection among 14 stallions following natural infections. The data showed that carrier stallions with a CD3+ T lymphocyte susceptibility phenotype to in vitro EAV infection may be at higher risk of becoming carriers than those that lack this phenotype (P=0.0002).

Original languageEnglish
Pages (from-to)12407-12410
Number of pages4
JournalJournal of Virology
Volume86
Issue number22
DOIs
StatePublished - Nov 2012

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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