TY - JOUR
T1 - Evolution of the wheat blast fungus through functional losses in a host specificity determinant
AU - Inoue, Yoshihiro
AU - Vy, Trinh T.P.
AU - Yoshida, Kentaro
AU - Asano, Hokuto
AU - Mitsuoka, Chikako
AU - Asuke, Soichiro
AU - Anh, Vu L.
AU - Cumagun, Christian J.R.
AU - Chuma, Izumi
AU - Terauchi, Ryohei
AU - Kato, Kenji
AU - Mitchell, Thomas
AU - Valent, Barbara
AU - Farman, Mark
AU - Tosa, Yukio
N1 - Publisher Copyright:
© 2017, American Association for the Advancement of Science. All rights reserved.
PY - 2017/7/7
Y1 - 2017/7/7
N2 - Wheat blast first emerged in Brazil in the mid-1980s and has recently caused heavy crop losses in Asia. Here we show how this devastating pathogen evolved in Brazil. Genetic analysis of host species determinants in the blast fungus resulted in the cloning of avirulence genes PWT3 and PWT4, whose gene products elicit defense in wheat cultivars containing the corresponding resistance genes Rwt3 and Rwt4. Studies on avirulence and resistance gene distributions, together with historical data on wheat cultivation in Brazil, suggest that wheat blast emerged due to widespread deployment of rwt3 wheat (susceptible to Lolium isolates), followed by the loss of function of PWT3. This implies that the rwt3 wheat served as a springboard for the host jump to common wheat.
AB - Wheat blast first emerged in Brazil in the mid-1980s and has recently caused heavy crop losses in Asia. Here we show how this devastating pathogen evolved in Brazil. Genetic analysis of host species determinants in the blast fungus resulted in the cloning of avirulence genes PWT3 and PWT4, whose gene products elicit defense in wheat cultivars containing the corresponding resistance genes Rwt3 and Rwt4. Studies on avirulence and resistance gene distributions, together with historical data on wheat cultivation in Brazil, suggest that wheat blast emerged due to widespread deployment of rwt3 wheat (susceptible to Lolium isolates), followed by the loss of function of PWT3. This implies that the rwt3 wheat served as a springboard for the host jump to common wheat.
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U2 - 10.1126/science.aam9654
DO - 10.1126/science.aam9654
M3 - Article
C2 - 28684523
AN - SCOPUS:85024129998
SN - 0036-8075
VL - 357
SP - 80
EP - 83
JO - Science
JF - Science
IS - 6346
ER -