Evolution of the wheat blast fungus through functional losses in a host specificity determinant

Yoshihiro Inoue; Trinh T.P. Vy; Kentaro Yoshida; Hokuto Asano; Chikako Mitsuoka; Soichiro Asuke; Vu L. Anh; Christian J.R. Cumagun; Izumi Chuma; Ryohei Terauchi; Kenji Kato; Thomas Mitchell; Barbara Valent; Mark Farman; Yukio Tosa

doi:10.1126/science.aam9654

Evolution of the wheat blast fungus through functional losses in a host specificity determinant

Yoshihiro Inoue, Trinh T.P. Vy, Kentaro Yoshida, Hokuto Asano, Chikako Mitsuoka, Soichiro Asuke, Vu L. Anh, Christian J.R. Cumagun, Izumi Chuma, Ryohei Terauchi, Kenji Kato, Thomas Mitchell, Barbara Valent, Mark Farman, Yukio Tosa

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205 Scopus citations

Abstract

Wheat blast first emerged in Brazil in the mid-1980s and has recently caused heavy crop losses in Asia. Here we show how this devastating pathogen evolved in Brazil. Genetic analysis of host species determinants in the blast fungus resulted in the cloning of avirulence genes PWT3 and PWT4, whose gene products elicit defense in wheat cultivars containing the corresponding resistance genes Rwt3 and Rwt4. Studies on avirulence and resistance gene distributions, together with historical data on wheat cultivation in Brazil, suggest that wheat blast emerged due to widespread deployment of rwt3 wheat (susceptible to Lolium isolates), followed by the loss of function of PWT3. This implies that the rwt3 wheat served as a springboard for the host jump to common wheat.

Original language	English
Pages (from-to)	80-83
Number of pages	4
Journal	Science
Volume	357
Issue number	6346
DOIs	https://doi.org/10.1126/science.aam9654
State	Published - Jul 7 2017

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© 2017, American Association for the Advancement of Science. All rights reserved.

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title = "Evolution of the wheat blast fungus through functional losses in a host specificity determinant",

abstract = "Wheat blast first emerged in Brazil in the mid-1980s and has recently caused heavy crop losses in Asia. Here we show how this devastating pathogen evolved in Brazil. Genetic analysis of host species determinants in the blast fungus resulted in the cloning of avirulence genes PWT3 and PWT4, whose gene products elicit defense in wheat cultivars containing the corresponding resistance genes Rwt3 and Rwt4. Studies on avirulence and resistance gene distributions, together with historical data on wheat cultivation in Brazil, suggest that wheat blast emerged due to widespread deployment of rwt3 wheat (susceptible to Lolium isolates), followed by the loss of function of PWT3. This implies that the rwt3 wheat served as a springboard for the host jump to common wheat.",

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AU - Inoue, Yoshihiro

AU - Vy, Trinh T.P.

AU - Yoshida, Kentaro

AU - Asano, Hokuto

AU - Mitsuoka, Chikako

AU - Asuke, Soichiro

AU - Anh, Vu L.

AU - Cumagun, Christian J.R.

AU - Chuma, Izumi

AU - Terauchi, Ryohei

AU - Kato, Kenji

AU - Mitchell, Thomas

AU - Valent, Barbara

AU - Farman, Mark

AU - Tosa, Yukio

PY - 2017/7/7

Y1 - 2017/7/7

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AB - Wheat blast first emerged in Brazil in the mid-1980s and has recently caused heavy crop losses in Asia. Here we show how this devastating pathogen evolved in Brazil. Genetic analysis of host species determinants in the blast fungus resulted in the cloning of avirulence genes PWT3 and PWT4, whose gene products elicit defense in wheat cultivars containing the corresponding resistance genes Rwt3 and Rwt4. Studies on avirulence and resistance gene distributions, together with historical data on wheat cultivation in Brazil, suggest that wheat blast emerged due to widespread deployment of rwt3 wheat (susceptible to Lolium isolates), followed by the loss of function of PWT3. This implies that the rwt3 wheat served as a springboard for the host jump to common wheat.

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Evolution of the wheat blast fungus through functional losses in a host specificity determinant

Abstract

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