Abstract
Delay discounting describes the devaluation of a reinforcer as a function of the delay until its receipt. Although all people discount delayed reinforcers, one consistent finding is that substance-dependent individuals tend to discount delayed reinforcers more rapidly than do healthy controls. Moreover, these higher-than-normal discounting rates have been observed in individuals with other behavioral maladies such as pathological gambling, poor health behavior, and overeating. This suggests that high rates of delay discounting may be a trans-disease process (i.e., a process that occurs across a range of disorders, making findings from one disorder relevant to other disorders). In this paper, we argue that delay discounting is a trans-disease process, undergirded by an imbalance between two competing neurobehavioral decision systems. Implications for our understanding of, and treatment for, this trans-disease process are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 287-297 |
| Number of pages | 11 |
| Journal | Pharmacology and Therapeutics |
| Volume | 134 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 2012 |
Bibliographical note
Funding Information:This work was supported by NIDA grants R01DA030241 ; R01DA024080 ; R01DA012997 ; and [NIAAA] R01DA024080-02S1 . The authors would like to thank Patsy Marshall for her assistance in manuscript preparation.
Funding
This work was supported by NIDA grants R01DA030241 ; R01DA024080 ; R01DA012997 ; and [NIAAA] R01DA024080-02S1 . The authors would like to thank Patsy Marshall for her assistance in manuscript preparation.
| Funders | Funder number |
|---|---|
| National Institute on Drug Abuse | R01DA024080, R01DA030241, R01DA012997, T32DA022981 |
| National Institute on Alcohol Abuse and Alcoholism |
Keywords
- Addiction
- Delay discounting
- Gambling
- Health behaviors
- Neuroscience
- Obesity
- Trans-disease process
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)