Exercise-induced pulmonary hemorrhage: A review of the etiology and pathogenesis

This paper reviews recent progress in the etiology and pathology of exercise-induced pulmonary hemorrhage (EIPH), a condition which poses an important cause of financial loss to the equine industry. It is hypothesized that all horses experience some grade of EIPH during strenuous exercise. In light of the inflammatory response in lung tissue following infusion of autologous blood and the chronic nature of EIPH in racing horses, every effort should be made to eliminate EIPH during exercise and to ameliorate the inflammatory response once hemorrhage has occurred.