Experimental determination of the TG-43 dosimetric characteristics of Echoseed™ model 6733 ¹²⁵I brachytherapy source

Recently an improved design of a ¹²⁵I brachytherapy source has been introduced for interstitial seed implants, particularly for prostate seed implants. This design improves the in situ ultrasound visualization of the source compared to the conventional seed. In this project, the TG-43 recommended dosimetric characteristics of the new brachytherapy source have been experimentally determined in Solid Water™ phantom material. The measured dosimetric characteristics of the new source have been compared with data reported in the literature for other source designs. The measured dose rate constant, Λ, in Solid Water was multiplied by 1.05 to extract the dose rate constant in water. The dose rate constant of the new source in water was found to be 0.99±8% cGy h^-1 U^-1. The radial dose function was measured at distances between 0.5 and 10 cm using LiF TLDs in Solid Water™ phantom. The anisotropy function, F(r, θ), was measured at distances of 2, 3, 5, and 7 cm.