Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents

William Marciel de Souza, Alex Martins Machado, Luiz Tadeu Moraes Figueiredo

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


This study shows an experimental spillover infection of Sigmodontinae rodents with Rio Mamore hantavirus (RIOMV). Necromys lasiurus and Akodon sp were infected with 103 RNA copies of RIOMV by intraperitoneal administration. The viral genome was detected in heart, lung, and kidney tissues 18 days after infection (ai), and viral excretion in urine and faeces began at four and six ai, respectively. These results reveal that urine and faeces of infected rodents contain the virus for at least 18 days. It is possible that inhaled aerosols of these excreta could transmit hantavirus to humans and other animals.

Original languageEnglish
Pages (from-to)399-402
Number of pages4
JournalMemorias do Instituto Oswaldo Cruz
Issue number6
StatePublished - Jun 2016

Bibliographical note

Publisher Copyright:
© 2016, Fundacao Oswaldo Cruz. All rights reserved.


  • Experimental infection
  • Rio Mamore hantavirus
  • Wild Sigmodontinae rodents

ASJC Scopus subject areas

  • Microbiology (medical)


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