Abstract
This study shows an experimental spillover infection of Sigmodontinae rodents with Rio Mamore hantavirus (RIOMV). Necromys lasiurus and Akodon sp were infected with 103 RNA copies of RIOMV by intraperitoneal administration. The viral genome was detected in heart, lung, and kidney tissues 18 days after infection (ai), and viral excretion in urine and faeces began at four and six ai, respectively. These results reveal that urine and faeces of infected rodents contain the virus for at least 18 days. It is possible that inhaled aerosols of these excreta could transmit hantavirus to humans and other animals.
| Original language | English |
|---|---|
| Pages (from-to) | 399-402 |
| Number of pages | 4 |
| Journal | Memorias do Instituto Oswaldo Cruz |
| Volume | 111 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2016 |
Bibliographical note
Publisher Copyright:© 2016, Fundacao Oswaldo Cruz. All rights reserved.
Funding
Financial support: FAPESP (grant n° 2008/50617-6, scholarship n° 11/05067-0, 12/24150-9, 09/17518-7), CNPq (301677/2013-1).
| Funders | Funder number |
|---|---|
| Fundação de Amparo à Pesquisa do Estado de São Paulo | 11/05067-0, 12/24150-9, 2008/50617-6, 09/17518-7 |
| Conselho Nacional de Desenvolvimento Científico e Tecnológico | 301677/2013-1 |
Keywords
- Experimental infection
- Rio Mamore hantavirus
- Wild Sigmodontinae rodents
ASJC Scopus subject areas
- Microbiology (medical)
Fingerprint
Dive into the research topics of 'Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver