Experimental Observations on the Relationship between Ethanol Tolerance and Physical Dependence

M. Rigby, J. M. Littleton

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The development of functional tolerance In ethanol has been studied in control mice and in mice which are physically dependent an ethanol. Physical dependence is associated with a state of submaximal functional tolerance. which can neither be increased nor reduced rapidly in response to altered tissue concentrations of the drug.

Original languageEnglish
Pages (from-to)363-367
Number of pages5
JournalBritish Journal of Addiction to Alcohol & Other Drugs
Volume74
Issue number4
DOIs
StatePublished - Dec 1979

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Psychiatry and Mental health

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