Expression of non-organelle glutamate transporters to support peripheral tissue function

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

4 Scopus citations


The goal of this chapter is to highlight some critical physiological relationships that exist among glutamate transport systems (biochemically defined activities), glutamate transporters (molecularly identified proteins capable of the biochemically defined activities), and the metabolism of glutamate by several peripheral (noncentral nervous system) tissues. Collectively, these processes account for much of the whole-body flux of nitrogen and carbon. Presented is (a) an overview of the importance of glutamate metabolism to the function of peripheral tissues, (b) molecular and functional characteristics, and expression patterns, of transport proteins capable of glutamate transport, (c) a detailed examination of how glutamate transport activities and proteins support the function of hepatic (mature and fetal), placental, white adipose, and muscle tissues, and (d) a listing of underexplored areas of research that this author thinks are important to more fully understand the integrated role of glutamate transport capacity and peripheral tissue function.

Original languageEnglish
Title of host publicationGlutamate Receptors in Peripheral Tissue
Subtitle of host publicationExcitatory Transmission Outside the CNS
Number of pages29
ISBN (Electronic)9780306486449
StatePublished - 2005

ASJC Scopus subject areas

  • Medicine (all)
  • Neuroscience (all)


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