Extended-release Buprenorphine Administered at Discharge in Hospitalized Persons With Opioid Use Disorder: A Case Series

Elizabeth Rose Hansen, Anna Maria South, Michelle R. Lofwall, Laura C. Fanucchi

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Monthly subcutaneous injectable buprenorphine (XR-Bup) is an option for treatment of opioid use disorder (OUD) that addresses some sublingual buprenorphine adherence barriers and is infrequently offered to hospitalized patients with OUD. Methods: A retrospective case series was performed for patients receiving XR-Bup upon discharge from 1 academic medical center. Demographic information, diagnoses, follow-up, and documented factors informing the selection of XR-Bup were extracted from the electronic health record. Results: In 1 year, 37 hospitalized patients with OUD received XR-Bup at discharge. The average age was 37.6 years, and patients were primarily Medicaid insured with an injection-related infection. The most common documented factors informing the selection of XR-Bup were as follows: previous sublingual buprenorphine adherence barriers, concurrent stimulant use disorder, and patient preference. Sixty-four percent of patients scheduled for follow-up attended appointments, and 55% received a second dose of XR-Bup. Conclusions: Subcutaneous injectable buprenorphine is an option for OUD treatment among hospitalized patients providing 30 or more days of buprenorphine coverage in the postdischarge period.

Original languageEnglish
Pages (from-to)65-67
Number of pages3
JournalJournal of Addiction Medicine
Volume18
Issue number1
DOIs
StatePublished - Jan 1 2024

Bibliographical note

Publisher Copyright:
Copyright © 2023 American Society of Addiction Medicine.

Keywords

  • extended-release buprenorphine
  • in-hospital treatment of OUD

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)

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