Extracorporeal membrane oxygenation versus conventional treatment: Neurodevelopmental and social outcomes at 24 months

Susan H. Landry; Lorene M. Knowles; Cynthia L. Miller-Loncar; Susan R. Wildin; Joseph B. Zwischenberger

doi:10.1076/chin.4.2.118.3186

Extracorporeal membrane oxygenation versus conventional treatment: Neurodevelopmental and social outcomes at 24 months

Susan H. Landry, Lorene M. Knowles, Cynthia L. Miller-Loncar, Susan R. Wildin, Joseph B. Zwischenberger

Research output: Contribution to journal › Article › peer-review

Abstract

The purpose of this prospective, controlled study was to compare neurodevelopmental and social outcomes at 2 years of age for children treated with extracorporeal membrane oxygenation (ECMO; n = 25) to those of children with severe respiratory illness treated with conventional methods (CT; n = 16) and to matched, healthy full-term (PT; n = 29) children. Mothers' parenting attitudes and children's mental, motor, language, exploratory play, and social competence skills were assessed. A retrospective chart review was also undertaken to further describe the groups with respect to the results of neuroimaging, audiologic, and neuromotor examinations. The FT group had significantly higher mental, motor, and language scores as compared to the ECMO and CT groups. Groups did not differ on measures of behavior, social competence, exploratory play skills, or parental attitudes. Specifically for the ECMO group, there was a trend toward language being more problematic than other areas of development. In general, the data demonstrate that severe respiratory complications, regardless of type of treatment, place children at increased risk for neurodevelopmental difficulties.

Original language	English
Pages (from-to)	118-130
Number of pages	13
Journal	Child Neuropsychology
Volume	4
Issue number	2
DOIs	https://doi.org/10.1076/chin.4.2.118.3186
State	Published - 1998

Bibliographical note

Funding Information:
* This project was funded in part by the John Sealy Memorial Endowment Fund. Special thanks to Annette Evans and Kathy Jeffcoat for their help with recruitment, scheduling, and coding, and to Jennifer Minor, Pamela Garner, and Tracy Jordan for child evaluations. Address correspondence to: Susan H. Landry, Department of Pediatrics, University of Texas Medical School, 6436 Fannin, Suite PV 608, Houston, TX 77030, USA. Accepted for publication: August 5, 1997.

Funding

* This project was funded in part by the John Sealy Memorial Endowment Fund. Special thanks to Annette Evans and Kathy Jeffcoat for their help with recruitment, scheduling, and coding, and to Jennifer Minor, Pamela Garner, and Tracy Jordan for child evaluations. Address correspondence to: Susan H. Landry, Department of Pediatrics, University of Texas Medical School, 6436 Fannin, Suite PV 608, Houston, TX 77030, USA. Accepted for publication: August 5, 1997.

Funders	Funder number
John Sealy Memorial Endowment Fund

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Neuropsychology and Physiological Psychology
Developmental and Educational Psychology

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10.1076/chin.4.2.118.3186

Cite this

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title = "Extracorporeal membrane oxygenation versus conventional treatment: Neurodevelopmental and social outcomes at 24 months",

abstract = "The purpose of this prospective, controlled study was to compare neurodevelopmental and social outcomes at 2 years of age for children treated with extracorporeal membrane oxygenation (ECMO; n = 25) to those of children with severe respiratory illness treated with conventional methods (CT; n = 16) and to matched, healthy full-term (PT; n = 29) children. Mothers' parenting attitudes and children's mental, motor, language, exploratory play, and social competence skills were assessed. A retrospective chart review was also undertaken to further describe the groups with respect to the results of neuroimaging, audiologic, and neuromotor examinations. The FT group had significantly higher mental, motor, and language scores as compared to the ECMO and CT groups. Groups did not differ on measures of behavior, social competence, exploratory play skills, or parental attitudes. Specifically for the ECMO group, there was a trend toward language being more problematic than other areas of development. In general, the data demonstrate that severe respiratory complications, regardless of type of treatment, place children at increased risk for neurodevelopmental difficulties.",

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AU - Zwischenberger, Joseph B.

N1 - Funding Information: * This project was funded in part by the John Sealy Memorial Endowment Fund. Special thanks to Annette Evans and Kathy Jeffcoat for their help with recruitment, scheduling, and coding, and to Jennifer Minor, Pamela Garner, and Tracy Jordan for child evaluations. Address correspondence to: Susan H. Landry, Department of Pediatrics, University of Texas Medical School, 6436 Fannin, Suite PV 608, Houston, TX 77030, USA. Accepted for publication: August 5, 1997.

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N2 - The purpose of this prospective, controlled study was to compare neurodevelopmental and social outcomes at 2 years of age for children treated with extracorporeal membrane oxygenation (ECMO; n = 25) to those of children with severe respiratory illness treated with conventional methods (CT; n = 16) and to matched, healthy full-term (PT; n = 29) children. Mothers' parenting attitudes and children's mental, motor, language, exploratory play, and social competence skills were assessed. A retrospective chart review was also undertaken to further describe the groups with respect to the results of neuroimaging, audiologic, and neuromotor examinations. The FT group had significantly higher mental, motor, and language scores as compared to the ECMO and CT groups. Groups did not differ on measures of behavior, social competence, exploratory play skills, or parental attitudes. Specifically for the ECMO group, there was a trend toward language being more problematic than other areas of development. In general, the data demonstrate that severe respiratory complications, regardless of type of treatment, place children at increased risk for neurodevelopmental difficulties.

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Extracorporeal membrane oxygenation versus conventional treatment: Neurodevelopmental and social outcomes at 24 months

Abstract

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