Abstract
Preterm infants with respiratory distress may require mechanical ventilation which is associated with increased pulmonary morbidities. Prompt and successful extubation to noninvasive support is a pressing goal. In this communication, we show original data that increased recurring intermittent hypoxemia (IH, oxygen saturation <80%) may be associated with extubation failure at 72 h in a cohort of neonates <30 weeks gestational age. Current-generation bedside high-resolution pulse oximeters provide saturation profiles that may be of use in identifying extubation readiness and failure. A larger prospective study that utilizes intermittent hypoxemia as an adjunct predictor for extubation readiness is warranted.
| Original language | English |
|---|---|
| Article number | 237 |
| Journal | Children |
| Volume | 8 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2021 |
Bibliographical note
Publisher Copyright:© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Funding
Funding: The study was funded in part by: (1) The Gerber Foundation (EGA, PI), (2) University of Kentucky’s National Center for Advancing Translational Sciences, UL1RR033173, and (3) TMR is supported by the NIH K08HL133459-04 grant. The study was funded in part by: (1) The Gerber Foundation (EGA, PI), (2) University of Kentucky?s National Center for Advancing Translational Sciences, UL1RR033173, and (3) TMR is supported by the NIH K08HL133459-04 grant.
| Funders | Funder number |
|---|---|
| EGA | |
| University of Kentucky?s National Center for Advancing Translational Sciences | |
| University of Kentucky’s National Center for Advancing Translational Sciences | UL1RR033173 |
| National Institutes of Health (NIH) | K08HL133459-04 |
| Gerber Foundation |
Keywords
- Extubation
- Intermittent hypoxemia
- Intubation
- Preterm
- Respiratory distress
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health