Feasibility of collecting saliva for biological verification of tobacco use status in dental practices and patients’ homes: Results from the national dental PBRN

doi:10.1922/CDH_4474Stoops03

Feasibility of collecting saliva for biological verification of tobacco use status in dental practices and patients’ homes: Results from the national dental PBRN

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Objective: To evaluate the feasibility of collecting and analyzing saliva samples from dental practices and patients’ homes for biochemical verification of tobacco use status. Basic research design: Sub-study within single-arm, multi-center, longitudinal clinical study. Clinical setting: Dental practices in the South Central region of the United States National Dental Practice-Based Research Network and patients’ homes. Participants: Fifty-five patients recruited from 30 dental practices. Interventions: Participants in the sub-study were instructed on saliva collection for cotinine analysis in dental practices where they enrolled in the primary study. Saliva was collected at the practices and then from patients’ homes. Main outcome measures: Feasibility for dental practice collection was define as 80% of enrolled participants having analyzable samples. For patients’ home collection, feasibility was defined as 70%. Results: Forty-seven samples (i.e., 86% of those enrolled) collected in dental practices were analyzable. Twenty-one samples (i.e. 38% of those enrolled) collected in patients’ homes were analyzable. Conclusions: Collecting saliva samples for cotinine analysis from dental practices, but not from patients’ homes, was feasible. Dental practices may provide an advantageous setting for biochemically verifying tobacco use status as part of clinical trials for tobacco cessation.

Original language	English
Pages (from-to)	187-189
Number of pages	3
Journal	Community Dental Health
Volume	36
Issue number	3
DOIs	https://doi.org/10.1922/CDH_4474Stoops03
State	Published - Sep 2019

Bibliographical note

Funding Information:
This project was funded by National Institutes of Health (NIH) grants R44-DE021327 and U19-DE022516. The authors gratefully acknowledge other Regional Coordinators who were involved with study development, protocol training of practitioners, and study implementation (Claudia Carcelén, MPH and Ellen Sowell, BA) as well as the network practice sites. Opinions and assertions contained herein are those of the authors and are not to be construed as necessarily representing the views of the respective organizations or the NIH. The informed consent of all human subjects who participated in this investigation was obtained after the nature of the procedures had been explained fully. This research was also supported by the Behavioral and Community-Based Research Shared Resource Facility (BCBR-SRF) of the University of Kentucky Markey Cancer Center (P30-CA177558). An Internet site devoted to details about the nation’s network is located at http://NationalDentalPBRN.org. Data collection forms, training instructions and a photograph of the saliva collection packet are available at http://nationaldentalpbrn.org/study-results/. The authors declare no conflicts of interest relevant to this work.

Publisher Copyright:
© BASCD 2019.

Keywords

Cotinine
Dental practice
Feasibility
Saliva
Smoking cessation

ASJC Scopus subject areas

Dentistry (all)
Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1922/CDH_4474Stoops03

Cite this

@article{4f3f492d8bbc4142aff76287c9789376,

title = "Feasibility of collecting saliva for biological verification of tobacco use status in dental practices and patients{\textquoteright} homes: Results from the national dental PBRN",

abstract = "Objective: To evaluate the feasibility of collecting and analyzing saliva samples from dental practices and patients{\textquoteright} homes for biochemical verification of tobacco use status. Basic research design: Sub-study within single-arm, multi-center, longitudinal clinical study. Clinical setting: Dental practices in the South Central region of the United States National Dental Practice-Based Research Network and patients{\textquoteright} homes. Participants: Fifty-five patients recruited from 30 dental practices. Interventions: Participants in the sub-study were instructed on saliva collection for cotinine analysis in dental practices where they enrolled in the primary study. Saliva was collected at the practices and then from patients{\textquoteright} homes. Main outcome measures: Feasibility for dental practice collection was define as 80% of enrolled participants having analyzable samples. For patients{\textquoteright} home collection, feasibility was defined as 70%. Results: Forty-seven samples (i.e., 86% of those enrolled) collected in dental practices were analyzable. Twenty-one samples (i.e. 38% of those enrolled) collected in patients{\textquoteright} homes were analyzable. Conclusions: Collecting saliva samples for cotinine analysis from dental practices, but not from patients{\textquoteright} homes, was feasible. Dental practices may provide an advantageous setting for biochemically verifying tobacco use status as part of clinical trials for tobacco cessation.",

keywords = "Cotinine, Dental practice, Feasibility, Saliva, Smoking cessation",

author = "Stoops, {William W.} and Johnson, {Meghan F.} and Strickland, {Justin C.} and Knudsen, {Hannah K.} and Gilbert, {Gregg H.} and Massingale, {Shermetria D.} and Ray, {Midge N.} and Studts, {Christina R.} and Lana Atchley and George Reynolds and Emily Slade and Studts, {Jamie L.}",

note = "Funding Information: This project was funded by National Institutes of Health (NIH) grants R44-DE021327 and U19-DE022516. The authors gratefully acknowledge other Regional Coordinators who were involved with study development, protocol training of practitioners, and study implementation (Claudia Carcel{\'e}n, MPH and Ellen Sowell, BA) as well as the network practice sites. Opinions and assertions contained herein are those of the authors and are not to be construed as necessarily representing the views of the respective organizations or the NIH. The informed consent of all human subjects who participated in this investigation was obtained after the nature of the procedures had been explained fully. This research was also supported by the Behavioral and Community-Based Research Shared Resource Facility (BCBR-SRF) of the University of Kentucky Markey Cancer Center (P30-CA177558). An Internet site devoted to details about the nation{\textquoteright}s network is located at http://NationalDentalPBRN.org. Data collection forms, training instructions and a photograph of the saliva collection packet are available at http://nationaldentalpbrn.org/study-results/. The authors declare no conflicts of interest relevant to this work. Publisher Copyright: {\textcopyright} BASCD 2019.",

year = "2019",

month = sep,

doi = "10.1922/CDH_4474Stoops03",

language = "English",

volume = "36",

pages = "187--189",

number = "3",

}

TY - JOUR

T1 - Feasibility of collecting saliva for biological verification of tobacco use status in dental practices and patients’ homes

T2 - Results from the national dental PBRN

AU - Stoops, William W.

AU - Johnson, Meghan F.

AU - Strickland, Justin C.

AU - Knudsen, Hannah K.

AU - Gilbert, Gregg H.

AU - Massingale, Shermetria D.

AU - Ray, Midge N.

AU - Studts, Christina R.

AU - Atchley, Lana

AU - Reynolds, George

AU - Slade, Emily

AU - Studts, Jamie L.

N1 - Funding Information: This project was funded by National Institutes of Health (NIH) grants R44-DE021327 and U19-DE022516. The authors gratefully acknowledge other Regional Coordinators who were involved with study development, protocol training of practitioners, and study implementation (Claudia Carcelén, MPH and Ellen Sowell, BA) as well as the network practice sites. Opinions and assertions contained herein are those of the authors and are not to be construed as necessarily representing the views of the respective organizations or the NIH. The informed consent of all human subjects who participated in this investigation was obtained after the nature of the procedures had been explained fully. This research was also supported by the Behavioral and Community-Based Research Shared Resource Facility (BCBR-SRF) of the University of Kentucky Markey Cancer Center (P30-CA177558). An Internet site devoted to details about the nation’s network is located at http://NationalDentalPBRN.org. Data collection forms, training instructions and a photograph of the saliva collection packet are available at http://nationaldentalpbrn.org/study-results/. The authors declare no conflicts of interest relevant to this work. Publisher Copyright: © BASCD 2019.

PY - 2019/9

Y1 - 2019/9

N2 - Objective: To evaluate the feasibility of collecting and analyzing saliva samples from dental practices and patients’ homes for biochemical verification of tobacco use status. Basic research design: Sub-study within single-arm, multi-center, longitudinal clinical study. Clinical setting: Dental practices in the South Central region of the United States National Dental Practice-Based Research Network and patients’ homes. Participants: Fifty-five patients recruited from 30 dental practices. Interventions: Participants in the sub-study were instructed on saliva collection for cotinine analysis in dental practices where they enrolled in the primary study. Saliva was collected at the practices and then from patients’ homes. Main outcome measures: Feasibility for dental practice collection was define as 80% of enrolled participants having analyzable samples. For patients’ home collection, feasibility was defined as 70%. Results: Forty-seven samples (i.e., 86% of those enrolled) collected in dental practices were analyzable. Twenty-one samples (i.e. 38% of those enrolled) collected in patients’ homes were analyzable. Conclusions: Collecting saliva samples for cotinine analysis from dental practices, but not from patients’ homes, was feasible. Dental practices may provide an advantageous setting for biochemically verifying tobacco use status as part of clinical trials for tobacco cessation.

AB - Objective: To evaluate the feasibility of collecting and analyzing saliva samples from dental practices and patients’ homes for biochemical verification of tobacco use status. Basic research design: Sub-study within single-arm, multi-center, longitudinal clinical study. Clinical setting: Dental practices in the South Central region of the United States National Dental Practice-Based Research Network and patients’ homes. Participants: Fifty-five patients recruited from 30 dental practices. Interventions: Participants in the sub-study were instructed on saliva collection for cotinine analysis in dental practices where they enrolled in the primary study. Saliva was collected at the practices and then from patients’ homes. Main outcome measures: Feasibility for dental practice collection was define as 80% of enrolled participants having analyzable samples. For patients’ home collection, feasibility was defined as 70%. Results: Forty-seven samples (i.e., 86% of those enrolled) collected in dental practices were analyzable. Twenty-one samples (i.e. 38% of those enrolled) collected in patients’ homes were analyzable. Conclusions: Collecting saliva samples for cotinine analysis from dental practices, but not from patients’ homes, was feasible. Dental practices may provide an advantageous setting for biochemically verifying tobacco use status as part of clinical trials for tobacco cessation.

KW - Cotinine

KW - Dental practice

KW - Feasibility

KW - Saliva

KW - Smoking cessation

UR - http://www.scopus.com/inward/record.url?scp=85071788834&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071788834&partnerID=8YFLogxK

U2 - 10.1922/CDH_4474Stoops03

DO - 10.1922/CDH_4474Stoops03

M3 - Article

C2 - 31436924

AN - SCOPUS:85071788834

SN - 0265-539X

VL - 36

SP - 187

EP - 189

JO - Community Dental Health

JF - Community Dental Health

IS - 3

ER -

Feasibility of collecting saliva for biological verification of tobacco use status in dental practices and patients’ homes: Results from the national dental PBRN

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this