Fecal transplantation does not transfer either susceptibility or resistance to food borne listeriosis in C57BL/6 and BALB/c/By mice

Sarah E.F. D'Orazio, Tanya Myers-Morales, Kate M. Bussell

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The composition of the intestinal microbiota has wide reaching effects on the health of an individual, including the development of protective innate immune responses. In this report, a fecal transplantation approach was used to determine whether resistance to food borne listeriosis was dependent on the murine gut microbiota. Transplantation of BALB/c/By feces did not increase the susceptibility of C57BL/6 mice to Listeria monocytogenes infection. Likewise, transplantation of C57BL/6 fecal matter did not enhance the resistance of BALB/c/By mice. Thus, intestinal microbiota composition is not a key factor that confers either susceptibility or resistance to food borne listeriosis in mice.

Original languageEnglish
Article number177.v1
JournalF1000Research
Volume2
DOIs
StatePublished - Aug 20 2013

Bibliographical note

Publisher Copyright:
© 2013 Myers-Morales T et al.

ASJC Scopus subject areas

  • General Immunology and Microbiology
  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology

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