Fluid intake, what's dopamine got to do with it?

Elizabeth G. Mietlicki-Baase, Jessica Santollo, Derek Daniels

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Maintaining fluid balance is critical for life. The central components that control fluid intake are only partly understood. This contribution to the collection of papers highlighting work by members of the Society for the Study of Ingestive Behavior focuses on the role that dopamine has on fluid intake and describes the roles that various bioregulators can have on thirst and sodium appetite by influencing dopamine systems in the brain. The goal of the review is to highlight areas in need of more research and to propose a framework to guide that research. We hope that this framework will inspire researchers in the field to investigate these interesting questions in order to form a more complete understanding of how fluid intake is controlled.

Original languageEnglish
Article number113418
JournalPhysiology and Behavior
StatePublished - Jul 1 2021

Bibliographical note

Funding Information:
We thank Jessica Tabman for collecting the data used to generate Fig. 2 and we are grateful that the editors invited us to contribute to this issue. This work was supported by a NARSAD Young Investigator Grant from the Brain & Behavior Research Foundation and a University at Buffalo Center for Ingestive Behavior Research Pilot Grant (EGM-B), NSF Grant 2019346 (JS), and NIH DK107500 (DD). EGM-B has received funding from Zealand Pharma and Boehringer-Ingelheim that was not used in support of this work. The order of appearance of the co-first authors was determined by a game of Buffalo themed trivia, in which Dr. Mietlicki-Baase decisively defeated Dr. Santollo by a score of 7–2.

Publisher Copyright:
© 2021


  • Angiotensin II
  • Mesolimbic
  • Sex differences
  • Sodium appetite
  • Thirst
  • Water intake

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience


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