Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome

Colin K. Grissom; Eliotte L. Hirshberg; Justin B. Dickerson; Samuel M. Brown; Michael J. Lanspa; Kathleen D. Liu; David Schoenfeld; Mark Tidswell; R. Duncan Hite; Peter Rock; Russell R. Miller; Alan H. Morris; L. Hudson; S. Gundel; C. Hough; M. Neff; K. Sims; A. Ungar; T. Watkins; J. Steingrub; M. Tidswell; E. Braden; L. DeSouza; J. Germain; C. Kardos; D. Kelley; L. Kozikowski; S. Ouellette; K. Guntupalli; V. Bandi; C. Pope; C. Ross; R. Brower; H. Fessler; D. Hager; P. Mendez-Tellez; D. Needham; K. Oakjones; J. Sevransky; A. Workneh; C. Shanholtz; D. Herr; H. Howes; G. Netzer; P. Rock; A. Sampaio; J. Titus; P. Sloane; T. Beck; H. Highfield; S. King; B. Lee; N. Bolouri; H. P. Wiedemann; R. W. Ashton; D. A. Culver; T. Frederick; J. A. Guzman; J. J. Komara; A. J. Reddy; R. Hejal; M. Andrews; D. Haney; A. F. Connors; S. Lasalvia; J. D. Thornton; E. L. Warren; M. Moss; E. L. Burnham; L. Gray; J. Maloney; M. Mealer; I. Douglas; K. Overdier; K. Thompson; R. Wolken; S. Frankel; J. McKeehan; M. L. Warner; T. Bost; C. Higgins; K. Hodgin; N. MacIntyre; L. Brown; C. Cox; M. Gentile; J. Govert; N. Knudsen; S. Carson; L. Chang; S. Choudhury; W. Hall; J. Lanier; A. P. Wheeler; G. R. Bernard; M. Hays; S. Mogan; T. Rice; R. D. Hite; K. Bender; A. Harvey; P. E. Morris; Mary Ragusky; P. Wright; S. Groce; J. McLean; A. Overton; J. Truwit; K. Enfield; M. Marshall; A. Morris; A. Austin; S. Barney; S. Brown; J. Ferguson; H. Gallo; T. Graydon; C. Grissom; E. Hirshberg; A. Jephson; N. Kumar; R. Miller; D. Murphy; J. Orme; A. Stowe; L. Struck; F. Thomas; D. Ward; L. Weaver; P. Bailey; W. Beninati; L. Bezdijan; T. Clemmer; S. Rimkus; R. Tanaka; C. Lawton; D. Hanselman; K. Sundar; W. Alward; C. Bishop; D. Eckley; T. Hill; B. Jensen; K. Ludwig; D. Nielsen; M. Pearce; M. A. Matthay; C. Calfee; B. Daniel; M. Eisner; O. Garcia; K. Kordesch; K. Liu; N. Shum; H. Zhou; M. W. Peterson; J. Blaauw; K. Van Gundy; T. Albertson; B. Morrissey; E. Vlastelin; R. Hubmayr; D. Brown; M. Dubin; E. Festic; O. Gajic; R. Hinds; S. Holets; D. Kor; A. Lee; M. Passe; G. Simpson; J. Wright; B. DeBoisblanc; A. Antoine; D. Charbonnet; J. Hunt; P. Lauto; A. Marr; G. Meyaski; C. Romaine; R. Tejedor; S. Brierre; J. Byrne; T. Jagneaux; C. LeBlanc; K. Moreau; C. Thomas; S. Jain; D. Taylor; L. Seoane; C. Hebert; J. Thompson; F. Simeone; J. Fearon; D. Schoenfeld; M. Guha; E. Hammond; N. Lavery; P. Lazar; R. Morse; C. Oldmixon; N. Ringwood; E. Smoot; B. T. Thompson; R. Wilson; A. Harabin; S. Bredow; M. Waclawiw; G. Weinmann

doi:10.1097/CCM.0000000000000715

Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome

Colin K. Grissom, Eliotte L. Hirshberg, Justin B. Dickerson, Samuel M. Brown, Michael J. Lanspa, Kathleen D. Liu, David Schoenfeld, Mark Tidswell, R. Duncan Hite, Peter Rock, Russell R. Miller, Alan H. Morris, L. Hudson, S. Gundel, C. Hough, M. Neff, K. Sims, A. Ungar, T. Watkins, J. SteingrubM. Tidswell, E. Braden, L. DeSouza, J. Germain, C. Kardos, D. Kelley, L. Kozikowski, S. Ouellette, K. Guntupalli, V. Bandi, C. Pope, C. Ross, R. Brower, H. Fessler, D. Hager, P. Mendez-Tellez, D. Needham, K. Oakjones, J. Sevransky, A. Workneh, C. Shanholtz, D. Herr, H. Howes, G. Netzer, P. Rock, A. Sampaio, J. Titus, P. Sloane, T. Beck, H. Highfield, S. King, B. Lee, N. Bolouri, H. P. Wiedemann, R. W. Ashton, D. A. Culver, T. Frederick, J. A. Guzman, J. J. Komara, A. J. Reddy, R. Hejal, M. Andrews, D. Haney, A. F. Connors, S. Lasalvia, J. D. Thornton, E. L. Warren, M. Moss, E. L. Burnham, L. Gray, J. Maloney, M. Mealer, I. Douglas, K. Overdier, K. Thompson, R. Wolken, S. Frankel, J. McKeehan, M. L. Warner, T. Bost, C. Higgins, K. Hodgin, N. MacIntyre, L. Brown, C. Cox, M. Gentile, J. Govert, N. Knudsen, S. Carson, L. Chang, S. Choudhury, W. Hall, J. Lanier, A. P. Wheeler, G. R. Bernard, M. Hays, S. Mogan, T. Rice, R. D. Hite, K. Bender, A. Harvey, P. E. Morris, Mary Ragusky, P. Wright, S. Groce, J. McLean, A. Overton, J. Truwit, K. Enfield, M. Marshall, A. Morris, A. Austin, S. Barney, S. Brown, J. Ferguson, H. Gallo, T. Graydon, C. Grissom, E. Hirshberg, A. Jephson, N. Kumar, R. Miller, D. Murphy, J. Orme, A. Stowe, L. Struck, F. Thomas, D. Ward, L. Weaver, P. Bailey, W. Beninati, L. Bezdijan, T. Clemmer, S. Rimkus, R. Tanaka, C. Lawton, D. Hanselman, K. Sundar, W. Alward, C. Bishop, D. Eckley, T. Hill, B. Jensen, K. Ludwig, D. Nielsen, M. Pearce, M. A. Matthay, C. Calfee, B. Daniel, M. Eisner, O. Garcia, K. Kordesch, K. Liu, N. Shum, H. Zhou, M. W. Peterson, J. Blaauw, K. Van Gundy, T. Albertson, B. Morrissey, E. Vlastelin, R. Hubmayr, D. Brown, M. Dubin, E. Festic, O. Gajic, R. Hinds, S. Holets, D. Kor, A. Lee, M. Passe, G. Simpson, J. Wright, B. DeBoisblanc, A. Antoine, D. Charbonnet, J. Hunt, P. Lauto, A. Marr, G. Meyaski, C. Romaine, R. Tejedor, S. Brierre, J. Byrne, T. Jagneaux, C. LeBlanc, K. Moreau, C. Thomas, S. Jain, D. Taylor, L. Seoane, C. Hebert, J. Thompson, F. Simeone, J. Fearon, D. Schoenfeld, M. Guha, E. Hammond, N. Lavery, P. Lazar, R. Morse, C. Oldmixon, N. Ringwood, E. Smoot, B. T. Thompson, R. Wilson, A. Harabin, S. Bredow, M. Waclawiw, G. Weinmann

Internal Medicine

Research output: Contribution to journal › Article › peer-review

110 Scopus citations

Abstract

Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.

Original language	English
Pages (from-to)	288-295
Number of pages	8
Journal	Critical Care Medicine
Volume	43
Issue number	2
DOIs	https://doi.org/10.1097/CCM.0000000000000715
State	Published - Feb 1 2015

Bibliographical note

Publisher Copyright:
© 2015 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins.

Funding

Funders	Funder number
American Society of Nephrology
American Thoracic Society
Intermountain Healthcare
National Institutes of Health (NIH)	HHSN268200536171C
National Institute of General Medical Sciences	K23GM094465
National Institute of General Medical Sciences

Keywords

Acute kidney injury
Adult respiratory distress syndrome
Clinical protocols
Critical illness
Fluid therapy
Shock

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine

Access to Document

10.1097/CCM.0000000000000715

Cite this

Grissom, C. K., Hirshberg, E. L., Dickerson, J. B., Brown, S. M., Lanspa, M. J., Liu, K. D., Schoenfeld, D., Tidswell, M., Hite, R. D., Rock, P., Miller, R. R., Morris, A. H., Hudson, L., Gundel, S., Hough, C., Neff, M., Sims, K., Ungar, A., Watkins, T., ... Weinmann, G. (2015). Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome. Critical Care Medicine, 43(2), 288-295. https://doi.org/10.1097/CCM.0000000000000715

@article{d3731d6f73c0463398562f64c9e6775e,

title = "Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome",

abstract = "Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.",

keywords = "Acute kidney injury, Adult respiratory distress syndrome, Clinical protocols, Critical illness, Fluid therapy, Shock",

author = "Grissom, {Colin K.} and Hirshberg, {Eliotte L.} and Dickerson, {Justin B.} and Brown, {Samuel M.} and Lanspa, {Michael J.} and Liu, {Kathleen D.} and David Schoenfeld and Mark Tidswell and Hite, {R. Duncan} and Peter Rock and Miller, {Russell R.} and Morris, {Alan H.} and L. Hudson and S. Gundel and C. Hough and M. Neff and K. Sims and A. Ungar and T. Watkins and J. Steingrub and M. Tidswell and E. Braden and L. DeSouza and J. Germain and C. Kardos and D. Kelley and L. Kozikowski and S. Ouellette and K. Guntupalli and V. Bandi and C. Pope and C. Ross and R. Brower and H. Fessler and D. Hager and P. Mendez-Tellez and D. Needham and K. Oakjones and J. Sevransky and A. Workneh and C. Shanholtz and D. Herr and H. Howes and G. Netzer and P. Rock and A. Sampaio and J. Titus and P. Sloane and T. Beck and H. Highfield and S. King and B. Lee and N. Bolouri and Wiedemann, {H. P.} and Ashton, {R. W.} and Culver, {D. A.} and T. Frederick and Guzman, {J. A.} and Komara, {J. J.} and Reddy, {A. J.} and R. Hejal and M. Andrews and D. Haney and Connors, {A. F.} and S. Lasalvia and Thornton, {J. D.} and Warren, {E. L.} and M. Moss and Burnham, {E. L.} and L. Gray and J. Maloney and M. Mealer and I. Douglas and K. Overdier and K. Thompson and R. Wolken and S. Frankel and J. McKeehan and Warner, {M. L.} and T. Bost and C. Higgins and K. Hodgin and N. MacIntyre and L. Brown and C. Cox and M. Gentile and J. Govert and N. Knudsen and S. Carson and L. Chang and S. Choudhury and W. Hall and J. Lanier and Wheeler, {A. P.} and Bernard, {G. R.} and M. Hays and S. Mogan and T. Rice and Hite, {R. D.} and K. Bender and A. Harvey and Morris, {P. E.} and Mary Ragusky and P. Wright and S. Groce and J. McLean and A. Overton and J. Truwit and K. Enfield and M. Marshall and A. Morris and A. Austin and S. Barney and S. Brown and J. Ferguson and H. Gallo and T. Graydon and C. Grissom and E. Hirshberg and A. Jephson and N. Kumar and R. Miller and D. Murphy and J. Orme and A. Stowe and L. Struck and F. Thomas and D. Ward and L. Weaver and P. Bailey and W. Beninati and L. Bezdijan and T. Clemmer and S. Rimkus and R. Tanaka and C. Lawton and D. Hanselman and K. Sundar and W. Alward and C. Bishop and D. Eckley and T. Hill and B. Jensen and K. Ludwig and D. Nielsen and M. Pearce and Matthay, {M. A.} and C. Calfee and B. Daniel and M. Eisner and O. Garcia and K. Kordesch and K. Liu and N. Shum and H. Zhou and Peterson, {M. W.} and J. Blaauw and {Van Gundy}, K. and T. Albertson and B. Morrissey and E. Vlastelin and R. Hubmayr and D. Brown and M. Dubin and E. Festic and O. Gajic and R. Hinds and S. Holets and D. Kor and A. Lee and M. Passe and G. Simpson and J. Wright and B. DeBoisblanc and A. Antoine and D. Charbonnet and J. Hunt and P. Lauto and A. Marr and G. Meyaski and C. Romaine and R. Tejedor and S. Brierre and J. Byrne and T. Jagneaux and C. LeBlanc and K. Moreau and C. Thomas and S. Jain and D. Taylor and L. Seoane and C. Hebert and J. Thompson and F. Simeone and J. Fearon and D. Schoenfeld and M. Guha and E. Hammond and N. Lavery and P. Lazar and R. Morse and C. Oldmixon and N. Ringwood and E. Smoot and Thompson, {B. T.} and R. Wilson and A. Harabin and S. Bredow and M. Waclawiw and G. Weinmann",

note = "Publisher Copyright: {\textcopyright} 2015 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins.",

year = "2015",

month = feb,

day = "1",

doi = "10.1097/CCM.0000000000000715",

language = "English",

volume = "43",

pages = "288--295",

number = "2",

}

Grissom, CK, Hirshberg, EL, Dickerson, JB, Brown, SM, Lanspa, MJ, Liu, KD, Schoenfeld, D, Tidswell, M, Hite, RD, Rock, P, Miller, RR, Morris, AH, Hudson, L, Gundel, S, Hough, C, Neff, M, Sims, K, Ungar, A, Watkins, T, Steingrub, J, Tidswell, M, Braden, E, DeSouza, L, Germain, J, Kardos, C, Kelley, D, Kozikowski, L, Ouellette, S, Guntupalli, K, Bandi, V, Pope, C, Ross, C, Brower, R, Fessler, H, Hager, D, Mendez-Tellez, P, Needham, D, Oakjones, K, Sevransky, J, Workneh, A, Shanholtz, C, Herr, D, Howes, H, Netzer, G, Rock, P, Sampaio, A, Titus, J, Sloane, P, Beck, T, Highfield, H, King, S, Lee, B, Bolouri, N, Wiedemann, HP, Ashton, RW, Culver, DA, Frederick, T, Guzman, JA, Komara, JJ, Reddy, AJ, Hejal, R, Andrews, M, Haney, D, Connors, AF, Lasalvia, S, Thornton, JD, Warren, EL, Moss, M, Burnham, EL, Gray, L, Maloney, J, Mealer, M, Douglas, I, Overdier, K, Thompson, K, Wolken, R, Frankel, S, McKeehan, J, Warner, ML, Bost, T, Higgins, C, Hodgin, K, MacIntyre, N, Brown, L, Cox, C, Gentile, M, Govert, J, Knudsen, N, Carson, S, Chang, L, Choudhury, S, Hall, W, Lanier, J, Wheeler, AP, Bernard, GR, Hays, M, Mogan, S, Rice, T, Hite, RD, Bender, K, Harvey, A, Morris, PE, Ragusky, M, Wright, P, Groce, S, McLean, J, Overton, A, Truwit, J, Enfield, K, Marshall, M, Morris, A, Austin, A, Barney, S, Brown, S, Ferguson, J, Gallo, H, Graydon, T, Grissom, C, Hirshberg, E, Jephson, A, Kumar, N, Miller, R, Murphy, D, Orme, J, Stowe, A, Struck, L, Thomas, F, Ward, D, Weaver, L, Bailey, P, Beninati, W, Bezdijan, L, Clemmer, T, Rimkus, S, Tanaka, R, Lawton, C, Hanselman, D, Sundar, K, Alward, W, Bishop, C, Eckley, D, Hill, T, Jensen, B, Ludwig, K, Nielsen, D, Pearce, M, Matthay, MA, Calfee, C, Daniel, B, Eisner, M, Garcia, O, Kordesch, K, Liu, K, Shum, N, Zhou, H, Peterson, MW, Blaauw, J, Van Gundy, K, Albertson, T, Morrissey, B, Vlastelin, E, Hubmayr, R, Brown, D, Dubin, M, Festic, E, Gajic, O, Hinds, R, Holets, S, Kor, D, Lee, A, Passe, M, Simpson, G, Wright, J, DeBoisblanc, B, Antoine, A, Charbonnet, D, Hunt, J, Lauto, P, Marr, A, Meyaski, G, Romaine, C, Tejedor, R, Brierre, S, Byrne, J, Jagneaux, T, LeBlanc, C, Moreau, K, Thomas, C, Jain, S, Taylor, D, Seoane, L, Hebert, C, Thompson, J, Simeone, F, Fearon, J, Schoenfeld, D, Guha, M, Hammond, E, Lavery, N, Lazar, P, Morse, R, Oldmixon, C, Ringwood, N, Smoot, E, Thompson, BT, Wilson, R, Harabin, A, Bredow, S, Waclawiw, M & Weinmann, G 2015, 'Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome', Critical Care Medicine, vol. 43, no. 2, pp. 288-295. https://doi.org/10.1097/CCM.0000000000000715

TY - JOUR

T1 - Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome

AU - Grissom, Colin K.

AU - Hirshberg, Eliotte L.

AU - Dickerson, Justin B.

AU - Brown, Samuel M.

AU - Lanspa, Michael J.

AU - Liu, Kathleen D.

AU - Schoenfeld, David

AU - Tidswell, Mark

AU - Hite, R. Duncan

AU - Rock, Peter

AU - Miller, Russell R.

AU - Morris, Alan H.

AU - Hudson, L.

AU - Gundel, S.

AU - Hough, C.

AU - Neff, M.

AU - Sims, K.

AU - Ungar, A.

AU - Watkins, T.

AU - Steingrub, J.

AU - Tidswell, M.

AU - Braden, E.

AU - DeSouza, L.

AU - Germain, J.

AU - Kardos, C.

AU - Kelley, D.

AU - Kozikowski, L.

AU - Ouellette, S.

AU - Guntupalli, K.

AU - Bandi, V.

AU - Pope, C.

AU - Ross, C.

AU - Brower, R.

AU - Fessler, H.

AU - Hager, D.

AU - Mendez-Tellez, P.

AU - Needham, D.

AU - Oakjones, K.

AU - Sevransky, J.

AU - Workneh, A.

AU - Shanholtz, C.

AU - Herr, D.

AU - Howes, H.

AU - Netzer, G.

AU - Rock, P.

AU - Sampaio, A.

AU - Titus, J.

AU - Sloane, P.

AU - Beck, T.

AU - Highfield, H.

AU - King, S.

AU - Lee, B.

AU - Bolouri, N.

AU - Wiedemann, H. P.

AU - Ashton, R. W.

AU - Culver, D. A.

AU - Frederick, T.

AU - Guzman, J. A.

AU - Komara, J. J.

AU - Reddy, A. J.

AU - Hejal, R.

AU - Andrews, M.

AU - Haney, D.

AU - Connors, A. F.

AU - Lasalvia, S.

AU - Thornton, J. D.

AU - Warren, E. L.

AU - Moss, M.

AU - Burnham, E. L.

AU - Gray, L.

AU - Maloney, J.

AU - Mealer, M.

AU - Douglas, I.

AU - Overdier, K.

AU - Thompson, K.

AU - Wolken, R.

AU - Frankel, S.

AU - McKeehan, J.

AU - Warner, M. L.

AU - Bost, T.

AU - Higgins, C.

AU - Hodgin, K.

AU - MacIntyre, N.

AU - Brown, L.

AU - Cox, C.

AU - Gentile, M.

AU - Govert, J.

AU - Knudsen, N.

AU - Carson, S.

AU - Chang, L.

AU - Choudhury, S.

AU - Hall, W.

AU - Lanier, J.

AU - Wheeler, A. P.

AU - Bernard, G. R.

AU - Hays, M.

AU - Mogan, S.

AU - Rice, T.

AU - Hite, R. D.

AU - Bender, K.

AU - Harvey, A.

AU - Morris, P. E.

AU - Ragusky, Mary

AU - Wright, P.

AU - Groce, S.

AU - McLean, J.

AU - Overton, A.

AU - Truwit, J.

AU - Enfield, K.

AU - Marshall, M.

AU - Morris, A.

AU - Austin, A.

AU - Barney, S.

AU - Brown, S.

AU - Ferguson, J.

AU - Gallo, H.

AU - Graydon, T.

AU - Grissom, C.

AU - Hirshberg, E.

AU - Jephson, A.

AU - Kumar, N.

AU - Miller, R.

AU - Murphy, D.

AU - Orme, J.

AU - Stowe, A.

AU - Struck, L.

AU - Thomas, F.

AU - Ward, D.

AU - Weaver, L.

AU - Bailey, P.

AU - Beninati, W.

AU - Bezdijan, L.

AU - Clemmer, T.

AU - Rimkus, S.

AU - Tanaka, R.

AU - Lawton, C.

AU - Hanselman, D.

AU - Sundar, K.

AU - Alward, W.

AU - Bishop, C.

AU - Eckley, D.

AU - Hill, T.

AU - Jensen, B.

AU - Ludwig, K.

AU - Nielsen, D.

AU - Pearce, M.

AU - Matthay, M. A.

AU - Calfee, C.

AU - Daniel, B.

AU - Eisner, M.

AU - Garcia, O.

AU - Kordesch, K.

AU - Liu, K.

AU - Shum, N.

AU - Zhou, H.

AU - Peterson, M. W.

AU - Blaauw, J.

AU - Van Gundy, K.

AU - Albertson, T.

AU - Morrissey, B.

AU - Vlastelin, E.

AU - Hubmayr, R.

AU - Brown, D.

AU - Dubin, M.

AU - Festic, E.

AU - Gajic, O.

AU - Hinds, R.

AU - Holets, S.

AU - Kor, D.

AU - Lee, A.

AU - Passe, M.

AU - Simpson, G.

AU - Wright, J.

AU - DeBoisblanc, B.

AU - Antoine, A.

AU - Charbonnet, D.

AU - Hunt, J.

AU - Lauto, P.

AU - Marr, A.

AU - Meyaski, G.

AU - Romaine, C.

AU - Tejedor, R.

AU - Brierre, S.

AU - Byrne, J.

AU - Jagneaux, T.

AU - LeBlanc, C.

AU - Moreau, K.

AU - Thomas, C.

AU - Jain, S.

AU - Taylor, D.

AU - Seoane, L.

AU - Hebert, C.

AU - Thompson, J.

AU - Simeone, F.

AU - Fearon, J.

AU - Schoenfeld, D.

AU - Guha, M.

AU - Hammond, E.

AU - Lavery, N.

AU - Lazar, P.

AU - Morse, R.

AU - Oldmixon, C.

AU - Ringwood, N.

AU - Smoot, E.

AU - Thompson, B. T.

AU - Wilson, R.

AU - Harabin, A.

AU - Bredow, S.

AU - Waclawiw, M.

AU - Weinmann, G.

PY - 2015/2/1

Y1 - 2015/2/1

N2 - Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.

AB - Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.

KW - Acute kidney injury

KW - Adult respiratory distress syndrome

KW - Clinical protocols

KW - Critical illness

KW - Fluid therapy

KW - Shock

UR - http://www.scopus.com/inward/record.url?scp=84925294058&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84925294058&partnerID=8YFLogxK

U2 - 10.1097/CCM.0000000000000715

DO - 10.1097/CCM.0000000000000715

M3 - Article

C2 - 25599463

AN - SCOPUS:84925294058

SN - 0090-3493

VL - 43

SP - 288

EP - 295

JO - Critical Care Medicine

JF - Critical Care Medicine

IS - 2

ER -

Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome

Abstract

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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