Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome

Colin K. Grissom, Eliotte L. Hirshberg, Justin B. Dickerson, Samuel M. Brown, Michael J. Lanspa, Kathleen D. Liu, David Schoenfeld, Mark Tidswell, R. Duncan Hite, Peter Rock, Russell R. Miller, Alan H. Morris, L. Hudson, S. Gundel, C. Hough, M. Neff, K. Sims, A. Ungar, T. Watkins, J. SteingrubM. Tidswell, E. Braden, L. DeSouza, J. Germain, C. Kardos, D. Kelley, L. Kozikowski, S. Ouellette, K. Guntupalli, V. Bandi, C. Pope, C. Ross, R. Brower, H. Fessler, D. Hager, P. Mendez-Tellez, D. Needham, K. Oakjones, J. Sevransky, A. Workneh, C. Shanholtz, D. Herr, H. Howes, G. Netzer, P. Rock, A. Sampaio, J. Titus, P. Sloane, T. Beck, H. Highfield, S. King, B. Lee, N. Bolouri, H. P. Wiedemann, R. W. Ashton, D. A. Culver, T. Frederick, J. A. Guzman, J. J. Komara, A. J. Reddy, R. Hejal, M. Andrews, D. Haney, A. F. Connors, S. Lasalvia, J. D. Thornton, E. L. Warren, M. Moss, E. L. Burnham, L. Gray, J. Maloney, M. Mealer, I. Douglas, K. Overdier, K. Thompson, R. Wolken, S. Frankel, J. McKeehan, M. L. Warner, T. Bost, C. Higgins, K. Hodgin, N. MacIntyre, L. Brown, C. Cox, M. Gentile, J. Govert, N. Knudsen, S. Carson, L. Chang, S. Choudhury, W. Hall, J. Lanier, A. P. Wheeler, G. R. Bernard, M. Hays, S. Mogan, T. Rice, R. D. Hite, K. Bender, A. Harvey, P. E. Morris, Mary Ragusky, P. Wright, S. Groce, J. McLean, A. Overton, J. Truwit, K. Enfield, M. Marshall, A. Morris, A. Austin, S. Barney, S. Brown, J. Ferguson, H. Gallo, T. Graydon, C. Grissom, E. Hirshberg, A. Jephson, N. Kumar, R. Miller, D. Murphy, J. Orme, A. Stowe, L. Struck, F. Thomas, D. Ward, L. Weaver, P. Bailey, W. Beninati, L. Bezdijan, T. Clemmer, S. Rimkus, R. Tanaka, C. Lawton, D. Hanselman, K. Sundar, W. Alward, C. Bishop, D. Eckley, T. Hill, B. Jensen, K. Ludwig, D. Nielsen, M. Pearce, M. A. Matthay, C. Calfee, B. Daniel, M. Eisner, O. Garcia, K. Kordesch, K. Liu, N. Shum, H. Zhou, M. W. Peterson, J. Blaauw, K. Van Gundy, T. Albertson, B. Morrissey, E. Vlastelin, R. Hubmayr, D. Brown, M. Dubin, E. Festic, O. Gajic, R. Hinds, S. Holets, D. Kor, A. Lee, M. Passe, G. Simpson, J. Wright, B. DeBoisblanc, A. Antoine, D. Charbonnet, J. Hunt, P. Lauto, A. Marr, G. Meyaski, C. Romaine, R. Tejedor, S. Brierre, J. Byrne, T. Jagneaux, C. LeBlanc, K. Moreau, C. Thomas, S. Jain, D. Taylor, L. Seoane, C. Hebert, J. Thompson, F. Simeone, J. Fearon, D. Schoenfeld, M. Guha, E. Hammond, N. Lavery, P. Lazar, R. Morse, C. Oldmixon, N. Ringwood, E. Smoot, B. T. Thompson, R. Wilson, A. Harabin, S. Bredow, M. Waclawiw, G. Weinmann

Research output: Contribution to journalArticlepeer-review

110 Scopus citations

Abstract

Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.

Original languageEnglish
Pages (from-to)288-295
Number of pages8
JournalCritical Care Medicine
Volume43
Issue number2
DOIs
StatePublished - Feb 1 2015

Bibliographical note

Publisher Copyright:
© 2015 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins.

Keywords

  • Acute kidney injury
  • Adult respiratory distress syndrome
  • Clinical protocols
  • Critical illness
  • Fluid therapy
  • Shock

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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