Functional utility of gold complexes with phosphorus donor ligands in biological systems

Adedamola S. Arojojoye, Samuel G. Awuah

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Metallo-phosphines are ubiquitous in organometallic chemistry with widespread applications as catalysts in various chemical transformations, precursors for organic electronics, and chemotherapeutic agents or chemical probes. Here, we provide a comprehensive review of the exploration of the current biological applications of Au complexes bearing phosphine donor ligands. The goal is to deepen our understanding of the synthetic utility and reactivity of Au-phosphine complexes to provide insights that could lead to the design of new molecules and enhance the cross-application or repurposing of these complexes.

Original languageEnglish
Article number216208
JournalCoordination Chemistry Reviews
Volume522
DOIs
StatePublished - Jan 1 2025

Bibliographical note

Publisher Copyright:
© 2024 Elsevier B.V.

Keywords

  • Biology
  • Bonding
  • Gold
  • Organometallic chemistry
  • Phosphorus

ASJC Scopus subject areas

  • General Chemistry
  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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