Abstract
Metallo-phosphines are ubiquitous in organometallic chemistry with widespread applications as catalysts in various chemical transformations, precursors for organic electronics, and chemotherapeutic agents or chemical probes. Here, we provide a comprehensive review of the exploration of the current biological applications of Au complexes bearing phosphine donor ligands. The goal is to deepen our understanding of the synthetic utility and reactivity of Au-phosphine complexes to provide insights that could lead to the design of new molecules and enhance the cross-application or repurposing of these complexes.
| Original language | English |
|---|---|
| Article number | 216208 |
| Journal | Coordination Chemistry Reviews |
| Volume | 522 |
| DOIs | |
| State | Published - Jan 1 2025 |
Bibliographical note
Publisher Copyright:© 2024 Elsevier B.V.
Funding
This work and S.G.A. was supported by grant R01CA258421-01 from the National Cancer Institute and NSF Grant No. 2203559.
| Funders | Funder number |
|---|---|
| National Childhood Cancer Registry – National Cancer Institute | |
| National Science Foundation Arctic Social Science Program | 2203559 |
Keywords
- Biology
- Bonding
- Gold
- Organometallic chemistry
- Phosphorus
ASJC Scopus subject areas
- General Chemistry
- Physical and Theoretical Chemistry
- Inorganic Chemistry
- Materials Chemistry
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