GDNF (including Nurturin)

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Clinical trials testing the trophic factors GDNF and NTRN for the treatment of Parkinson's disease have had mixed results. Analysis of the differences between the successful and unsuccessful trials strongly suggests that efficacious therapeutic approaches require controlled, site-specific delivery of trophic factors using methodology to optimize target tissue distribution.

Original languageEnglish
Title of host publicationEncyclopedia of Movement Disorders
Number of pages4
ISBN (Electronic)9780123741059
StatePublished - Jan 1 2010

Bibliographical note

Publisher Copyright:
© 2010 Elsevier Ltd. All rights reserved.


  • AAV2-neurturin
  • Clinical trial
  • GDNF
  • Neuroprotection
  • Neurorestoration
  • Neurturin
  • Parkinson's disease
  • Putamen
  • Substantia nigra

ASJC Scopus subject areas

  • General Medicine
  • General Neuroscience


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