Abstract
The laboratory axolotl (Ambystoma mexicanum) is widely used in biological research. Recent advancements in genetic and molecular toolkits are greatly accelerating the work using axolotl, especially in the area of tissue regeneration. At this juncture, there is a critical need to establish gene and transgenic nomenclature to ensure uniformity in axolotl research. Here, we propose guidelines for genetic nomenclature when working with the axolotl.
| Original language | English |
|---|---|
| Pages (from-to) | 913-921 |
| Number of pages | 9 |
| Journal | Developmental Dynamics |
| Volume | 251 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2022 |
Bibliographical note
Publisher Copyright:© 2021 The Authors. Developmental Dynamics published by Wiley Periodicals LLC on behalf of American Association of Anatomists.
Funding
Austrian Science Fund, Grant/Award Number: Standalone I4353; Deutsche Forschungsgemeinschaft, Grant/Award Number: 429469366; H2020 European Research Council, Grant/Award Number: AdG 742046; Key‐Area Research and Development Program of Guangdong Province, Grant/Award Numbers: 2018B030332001, 2019B030335001; National Institutes of Health, Grant/Award Numbers: 5P20GM104318‐08, P40 OD019794, R24OD010435; National Key R&D Program of China, Grant/Award Number: 2019YFE0106700; Natural Science Foundation of China, Grant/Award Number: 31970782 Funding information This system of nomenclature was discussed among salamander community and we thank all our colleagues for their inputs on developing these guidelines. The authors specially thank Anna Vlasova, Tamsin Jones, and Elspeth Bruford for their helpful suggestions regarding homologs and gene naming. Work in the JFF laboratory is supported by grants from National Key R&D Program of China 2019YFE0106700, the Natural Science Foundation of China 31970782, Key‐Area Research and Development Program of Guangdong Province 2018B030332001, 2019B030335001. Work in the SRV laboratory is supported by grants from the National Institutes of Health (P40 OD019794, R24OD010435). Work in the EMT laboratory is supported by grants from ERC (AdG 742046) and FWF (Standalone I4353). Work in the PM laboratory is supported by grants from National Institutes of Health—COBRE (5P20GM104318‐08) and DFG (429469366). Open Access funding enabled and organized by Projekt DEAL. This system of nomenclature was discussed among salamander community and we thank all our colleagues for their inputs on developing these guidelines. The authors specially thank Anna Vlasova, Tamsin Jones, and Elspeth Bruford for their helpful suggestions regarding homologs and gene naming. Work in the JFF laboratory is supported by grants from National Key R&D Program of China 2019YFE0106700, the Natural Science Foundation of China 31970782, Key-Area Research and Development Program of Guangdong Province 2018B030332001, 2019B030335001. Work in the SRV laboratory is supported by grants from the National Institutes of Health (P40 OD019794, R24OD010435). Work in the EMT laboratory is supported by grants from ERC (AdG 742046) and FWF (Standalone I4353). Work in the PM laboratory is supported by grants from National Institutes of Health—COBRE (5P20GM104318-08) and DFG (429469366). Open Access funding enabled and organized by Projekt DEAL.
| Funders | Funder number |
|---|---|
| Corporacion Nacional del Cobre | 5P20GM104318-08 |
| National Institutes of Health (NIH) | R24OD010435, 5P20GM104318‐08 |
| NIH Office of the Director | P40OD019794 |
| H2020 European Research Council | AdG 742046 |
| National Council for Eurasian and East European Research | |
| Deutsche Forschungsgemeinschaft | 429469366 |
| National Natural Science Foundation of China (NSFC) | 31970782 |
| Austrian Science Fund | I4353 |
| National Key Research and Development Program of China | 2019YFE0106700 |
| Special Project for Research and Development in Key areas of Guangdong Province | 2019B030335001, 2018B030332001 |
Keywords
- Gene
- nomenclature guidelines
- targeted mutations
- transgenics
ASJC Scopus subject areas
- Developmental Biology