Generic antiepileptic drug prescribing: A cross-sectional study

Jennifer Meyer; David Fardo; Steven T. Fleming; Claudia Hopenhayn; Yevgeniya Gokun; Melody Ryan

doi:10.1016/j.yebeh.2012.10.010

Generic antiepileptic drug prescribing: A cross-sectional study

Jennifer Meyer, David Fardo, Steven T. Fleming, Claudia Hopenhayn, Yevgeniya Gokun, Melody Ryan

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The use of generic antiepileptic drugs (AEDs) in patients with epilepsy is controversial. The purpose of this study is to identify patient characteristics associated with increased odds of receiving a generic AED product. A large commercial database was used to identify patients with a primary diagnosis of epilepsy who were prescribed an AED during a three-month window. Data analysis found that those ≥ 65. years old had 15.7% greater odds of receiving a generic AED (OR = 1.157; 95% CI = 1.056-1.268). Patients with Medicaid were found to have 2.44 times the odds of having had a generic AED prescription (OR = 2.44; CI = 2.168-2.754). Patients residing in the Northeast had 12.6% decreased odds of receiving a generic AED (OR = 0.874; CI = 0.821-0.931). These patient characteristics could signify certain health care disparities and may represent potential confounders to future observational studies.

Original language	English
Pages (from-to)	1-6
Number of pages	6
Journal	Epilepsy and Behavior
Volume	26
Issue number	1
DOIs	https://doi.org/10.1016/j.yebeh.2012.10.010
State	Published - Jan 2013

Bibliographical note

Funding Information:
The project described was supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health through Grant UL1RR033173 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Funding

The project described was supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health through Grant UL1RR033173 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Funders	Funder number
National Institutes of Health (NIH)
National Center for Research Resources	UL1RR033173
National Center for Research Resources
National Center for Advancing Translational Sciences (NCATS)	UL1TR001998
National Center for Advancing Translational Sciences (NCATS)

Keywords

Antiepileptic drugs
Cross-sectional
Epilepsy
Generic drugs
Prescribing

ASJC Scopus subject areas

Neurology
Clinical Neurology
Behavioral Neuroscience

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10.1016/j.yebeh.2012.10.010

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title = "Generic antiepileptic drug prescribing: A cross-sectional study",

abstract = "The use of generic antiepileptic drugs (AEDs) in patients with epilepsy is controversial. The purpose of this study is to identify patient characteristics associated with increased odds of receiving a generic AED product. A large commercial database was used to identify patients with a primary diagnosis of epilepsy who were prescribed an AED during a three-month window. Data analysis found that those ≥ 65. years old had 15.7\% greater odds of receiving a generic AED (OR = 1.157; 95\% CI = 1.056-1.268). Patients with Medicaid were found to have 2.44 times the odds of having had a generic AED prescription (OR = 2.44; CI = 2.168-2.754). Patients residing in the Northeast had 12.6\% decreased odds of receiving a generic AED (OR = 0.874; CI = 0.821-0.931). These patient characteristics could signify certain health care disparities and may represent potential confounders to future observational studies.",

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note = "Funding Information: The project described was supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health through Grant UL1RR033173 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. ",

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AU - Fardo, David

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AU - Gokun, Yevgeniya

AU - Ryan, Melody

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N2 - The use of generic antiepileptic drugs (AEDs) in patients with epilepsy is controversial. The purpose of this study is to identify patient characteristics associated with increased odds of receiving a generic AED product. A large commercial database was used to identify patients with a primary diagnosis of epilepsy who were prescribed an AED during a three-month window. Data analysis found that those ≥ 65. years old had 15.7% greater odds of receiving a generic AED (OR = 1.157; 95% CI = 1.056-1.268). Patients with Medicaid were found to have 2.44 times the odds of having had a generic AED prescription (OR = 2.44; CI = 2.168-2.754). Patients residing in the Northeast had 12.6% decreased odds of receiving a generic AED (OR = 0.874; CI = 0.821-0.931). These patient characteristics could signify certain health care disparities and may represent potential confounders to future observational studies.

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Generic antiepileptic drug prescribing: A cross-sectional study

Abstract

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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