Genetic basis for the origin of cardiac arrhythmias: Implications for therapy

Mackenzi Mbai; Sridharan Rajamani; Brian P. Delisle; Blake D. Anson; Corey Anderson; Jonathan C. Makielski; Craig T. January

doi:10.1007/s11886-002-0041-5

Genetic basis for the origin of cardiac arrhythmias: Implications for therapy

Mackenzi Mbai, Sridharan Rajamani, Brian P. Delisle, Blake D. Anson, Corey Anderson, Jonathan C. Makielski, Craig T. January

Physiology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The recognition of the role that genetic abnormalities play in the generation of cardiac arrhythmias and sudden cardiac death has evolved enormously over the past decade. One result is new insight into underlying physiologic and pathophysiologic mechanisms. New therapies based on this evolving insight are being developed. This review summarizes recent discoveries with a focus on the genetic basis of cardiac arrhythmias and their implications for new therapies.

Original language	English
Pages (from-to)	411-417
Number of pages	7
Journal	Current Cardiology Reports
Volume	4
Issue number	5
DOIs	https://doi.org/10.1007/s11886-002-0041-5
State	Published - 2002

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1007/s11886-002-0041-5

Cite this

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abstract = "The recognition of the role that genetic abnormalities play in the generation of cardiac arrhythmias and sudden cardiac death has evolved enormously over the past decade. One result is new insight into underlying physiologic and pathophysiologic mechanisms. New therapies based on this evolving insight are being developed. This review summarizes recent discoveries with a focus on the genetic basis of cardiac arrhythmias and their implications for new therapies.",

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AU - Makielski, Jonathan C.

AU - January, Craig T.

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AB - The recognition of the role that genetic abnormalities play in the generation of cardiac arrhythmias and sudden cardiac death has evolved enormously over the past decade. One result is new insight into underlying physiologic and pathophysiologic mechanisms. New therapies based on this evolving insight are being developed. This review summarizes recent discoveries with a focus on the genetic basis of cardiac arrhythmias and their implications for new therapies.

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Genetic basis for the origin of cardiac arrhythmias: Implications for therapy

Abstract

ASJC Scopus subject areas

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