Genetic implications in orthodontic tooth movement

James K. Hartsfield, Lorri Ann Morford

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


In orthodontics there is an interest in understanding how orthodontic tooth movement (OTM) may be modifi ed with the use of differential anchorage and decreasing treatment time(s). While the focus of these efforts has been on how various procedures or devices affect OTM (i.e., typically increase OTM), there has been little discussion of how the patient’s genetic background may infl uence variation in OTM. In this chapter, the clinician will be introduced to basic concepts of clinical genetics to gain insight into various genetic factors that infl uence bone modeling/remodeling and OTM. We describe how the genetic factors in these important pathways may also infl uence external apical root resorption (EARR) concurrent with OTM. At the end of the chapter, known genetic factors in two conditions that could secondarily affect OTM as they increase treatment complexity (dental primary failure of eruption and dental agenesis) are reviewed, and a select group of syndromes and other genetic conditions that may affect OTM in patients are also summarized.

Original languageEnglish
Title of host publicationBiology of Orthodontic Tooth Movement
Subtitle of host publicationCurrent Concepts and Applications in Orthodontic Practice
Number of pages30
ISBN (Electronic)9783319266091
StatePublished - Jan 1 2016

ASJC Scopus subject areas

  • Dentistry (all)


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