Genome editing in pests: basic science to applications

Research output: Contribution to journalReview articlepeer-review

Abstract

Recent developments in sequencing technologies produced enormous data on gene sequences and the identity of genes in many pest insects and disease vectors. However, the function of many of these genes is unknown. Functional genomics studies to uncover gene function in pest insects are urgently needed. RNA interference methods could be used in some insects but not most due to their variable efficiency among insect pests. Recently developed clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system of genome editing method is being developed for use in many insect pests. This technology has already been demonstrated to function in more than 40 insect pest species from seven orders and has contributed to advances in pest biology and the development of improved pest management methods. This review summarizes recent results of CRISPR/Cas9 technology developments and their contributions to advancing the basic and applied science of insect pests and disease vectors.

Original languageEnglish
JournalJournal of Pest Science
DOIs
StateAccepted/In press - 2024

Bibliographical note

Publisher Copyright:
© 2024, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Keywords

  • CRISPR/Cas9
  • Genetic control
  • Genome editing
  • Insect pests
  • Insecticide resistance
  • Pest biology

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Ecology
  • Agronomy and Crop Science
  • Plant Science
  • Insect Science

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