Getting to the core of atherosclerosis

Nancy R. Webb

doi:10.1038/nm1008-1015

Getting to the core of atherosclerosis

Nancy R. Webb

Pharmacology and Nutritional Sciences

Research output: Contribution to journal › Short survey › peer-review

20 Scopus citations

Abstract

For years, researchers have debated whether the enzyme lipoprotein- associated phospholipase A₂ (Lp-PLA₂), produced by inflammatory cells, is a 'good guy' or 'bad guy' in atherosclerosis. Work in pigs provides strong support for the view that Lp-PLA₂ promotes the formation of atherosclerotic lesions and dangerous, unstable atherosclerotic plaques (pages 1059-1066).

Original language	English
Pages (from-to)	1015-1016
Number of pages	2
Journal	Nature Medicine
Volume	14
Issue number	10
DOIs	https://doi.org/10.1038/nm1008-1015
State	Published - Oct 2008

Funding

Funders	Funder number
National Heart, Lung, and Blood Institute (NHLBI)	R01HL071098

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1038/nm1008-1015

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title = "Getting to the core of atherosclerosis",

abstract = "For years, researchers have debated whether the enzyme lipoprotein- associated phospholipase A2 (Lp-PLA2), produced by inflammatory cells, is a 'good guy' or 'bad guy' in atherosclerosis. Work in pigs provides strong support for the view that Lp-PLA2 promotes the formation of atherosclerotic lesions and dangerous, unstable atherosclerotic plaques (pages 1059-1066).",

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AB - For years, researchers have debated whether the enzyme lipoprotein- associated phospholipase A2 (Lp-PLA2), produced by inflammatory cells, is a 'good guy' or 'bad guy' in atherosclerosis. Work in pigs provides strong support for the view that Lp-PLA2 promotes the formation of atherosclerotic lesions and dangerous, unstable atherosclerotic plaques (pages 1059-1066).

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JO - Nature Medicine

JF - Nature Medicine

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Getting to the core of atherosclerosis

Abstract

Funding

ASJC Scopus subject areas

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