TY - JOUR
T1 - Giant basal cell carcinoma surgical management and reconstructive challenges
AU - Lackey, Phillip L.
AU - Sargent, Larry A.
AU - Wong, Lesley
AU - Brzezienski, Mark
AU - Kennedy, J. Woodfin
PY - 2007/3
Y1 - 2007/3
N2 - Basal cell carcinoma is exceedingly common, but tumors >5 cm in size or giant basal cell carcinomas (GBCCs) are rare. We retrospectively review 10 GBCCs in 8 patients treated by aggressive surgical excision and reconstruction in a single operative procedure. With the exception of 1 chest lesion, all GBCCs involved the face or scalp. The 10 large defects were reconstructed with 5 free-tissue transfers, 2 pedicled musculocutaneous flaps, and 3 rotational skin flaps. There has been no evidence of local recurrence or metastasis in a mean follow-up of 29 months. Neglect has a well-established role in the presence of GBCCs, with undiagnosed preexisting medical problems also common. Surgical excision and reconstruction is the treatment of choice and can be readily accomplished in a single procedure with few complications, good oncologic control, and acceptable cosmetic results.
AB - Basal cell carcinoma is exceedingly common, but tumors >5 cm in size or giant basal cell carcinomas (GBCCs) are rare. We retrospectively review 10 GBCCs in 8 patients treated by aggressive surgical excision and reconstruction in a single operative procedure. With the exception of 1 chest lesion, all GBCCs involved the face or scalp. The 10 large defects were reconstructed with 5 free-tissue transfers, 2 pedicled musculocutaneous flaps, and 3 rotational skin flaps. There has been no evidence of local recurrence or metastasis in a mean follow-up of 29 months. Neglect has a well-established role in the presence of GBCCs, with undiagnosed preexisting medical problems also common. Surgical excision and reconstruction is the treatment of choice and can be readily accomplished in a single procedure with few complications, good oncologic control, and acceptable cosmetic results.
KW - Basal cell carcinoma
KW - Giant basal cell
UR - http://www.scopus.com/inward/record.url?scp=34247641149&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34247641149&partnerID=8YFLogxK
U2 - 10.1097/01.sap.0000250842.96272.37
DO - 10.1097/01.sap.0000250842.96272.37
M3 - Review article
C2 - 17471127
AN - SCOPUS:34247641149
SN - 0148-7043
VL - 58
SP - 250
EP - 254
JO - Annals of Plastic Surgery
JF - Annals of Plastic Surgery
IS - 3
ER -