Giant basal cell carcinoma surgical management and reconstructive challenges

Phillip L. Lackey, Larry A. Sargent, Lesley Wong, Mark Brzezienski, J. Woodfin Kennedy

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations


Basal cell carcinoma is exceedingly common, but tumors >5 cm in size or giant basal cell carcinomas (GBCCs) are rare. We retrospectively review 10 GBCCs in 8 patients treated by aggressive surgical excision and reconstruction in a single operative procedure. With the exception of 1 chest lesion, all GBCCs involved the face or scalp. The 10 large defects were reconstructed with 5 free-tissue transfers, 2 pedicled musculocutaneous flaps, and 3 rotational skin flaps. There has been no evidence of local recurrence or metastasis in a mean follow-up of 29 months. Neglect has a well-established role in the presence of GBCCs, with undiagnosed preexisting medical problems also common. Surgical excision and reconstruction is the treatment of choice and can be readily accomplished in a single procedure with few complications, good oncologic control, and acceptable cosmetic results.

Original languageEnglish
Pages (from-to)250-254
Number of pages5
JournalAnnals of Plastic Surgery
Issue number3
StatePublished - Mar 2007


  • Basal cell carcinoma
  • Giant basal cell

ASJC Scopus subject areas

  • Surgery


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