Gliomas and Farm Pesticide Exposure in Men: The Upper Midwest Health Study

Avima M. Ruder; Martha A. Waters; Mary Ann Butler; Tania Carreón; Geoffrey M. Calvert; Karen E. Davis-King; Paul A. Schulte; Wayne T. Sanderson; Elizabeth M. Ward; L. Barbara Connally; Ellen F. Heineman; Jack S. Mandel; Roscoe F. Morton; Douglas J. Reding; Kenneth D. Rosenman; Glenn Talaska

doi:10.1080/00039890409602949

Gliomas and Farm Pesticide Exposure in Men: The Upper Midwest Health Study

Avima M. Ruder, Martha A. Waters, Mary Ann Butler, Tania Carreón, Geoffrey M. Calvert, Karen E. Davis-King, Paul A. Schulte, Wayne T. Sanderson, Elizabeth M. Ward, L. Barbara Connally, Ellen F. Heineman, Jack S. Mandel, Roscoe F. Morton, Douglas J. Reding, Kenneth D. Rosenman, Glenn Talaska

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

The National Institute for Occupational Safety and Health evaluated farm pesticide exposure and glioma risk in a study that included 457 glioma cases and 648 population-based controls, all adult men (18–80 yr old) and nonmetropolitan residents of Iowa, Michigan, Minnesota, and Wisconsin. Multiple logistic regressions were used to control for farm residence, age, age group, education, and exposure to other pesticides. No associations were found between glioma and 12 specific pesticides. We estimated adjusted odds ratios (ORs) and 95% confidence intervals (Cls) and found reduced glioma risk for insecticides (OR = 0.53, Cl = 0.37–0.77), fumigants (OR = 0.57, Cl = 0.34–0.95), and organochlorines (OR = 0.66, Cl = 0.47–0.94). In analyses excluding proxy respondents (47% of cases) most Cls included 1.0. No positive association of farm pesticide exposure and glioma was found. Other farm exposures may explain the excess brain cancer risk seen in previous studies.

Original language	English
Pages (from-to)	650-657
Number of pages	8
Journal	Archives of Environmental Health
Volume	59
Issue number	12
DOIs	https://doi.org/10.1080/00039890409602949
State	Published - Dec 2004

Keywords

Agricultural workers' diseases
Case-control studies
Glioma
Pesticides
Rural population

ASJC Scopus subject areas

Environmental Chemistry
General Environmental Science
Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/00039890409602949

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Ruder, A. M., Waters, M. A., Butler, M. A., Carreón, T., Calvert, G. M., Davis-King, K. E., Schulte, P. A., Sanderson, W. T., Ward, E. M., Connally, L. B., Heineman, E. F., Mandel, J. S., Morton, R. F., Reding, D. J., Rosenman, K. D., & Talaska, G. (2004). Gliomas and Farm Pesticide Exposure in Men: The Upper Midwest Health Study. Archives of Environmental Health, 59(12), 650-657. https://doi.org/10.1080/00039890409602949

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abstract = "The National Institute for Occupational Safety and Health evaluated farm pesticide exposure and glioma risk in a study that included 457 glioma cases and 648 population-based controls, all adult men (18–80 yr old) and nonmetropolitan residents of Iowa, Michigan, Minnesota, and Wisconsin. Multiple logistic regressions were used to control for farm residence, age, age group, education, and exposure to other pesticides. No associations were found between glioma and 12 specific pesticides. We estimated adjusted odds ratios (ORs) and 95% confidence intervals (Cls) and found reduced glioma risk for insecticides (OR = 0.53, Cl = 0.37–0.77), fumigants (OR = 0.57, Cl = 0.34–0.95), and organochlorines (OR = 0.66, Cl = 0.47–0.94). In analyses excluding proxy respondents (47% of cases) most Cls included 1.0. No positive association of farm pesticide exposure and glioma was found. Other farm exposures may explain the excess brain cancer risk seen in previous studies.",

keywords = "Agricultural workers' diseases, Case-control studies, Glioma, Pesticides, Rural population",

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Ruder, AM, Waters, MA, Butler, MA, Carreón, T, Calvert, GM, Davis-King, KE, Schulte, PA, Sanderson, WT, Ward, EM, Connally, LB, Heineman, EF, Mandel, JS, Morton, RF, Reding, DJ, Rosenman, KD & Talaska, G 2004, 'Gliomas and Farm Pesticide Exposure in Men: The Upper Midwest Health Study', Archives of Environmental Health, vol. 59, no. 12, pp. 650-657. https://doi.org/10.1080/00039890409602949

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T1 - Gliomas and Farm Pesticide Exposure in Men

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AU - Ruder, Avima M.

AU - Waters, Martha A.

AU - Butler, Mary Ann

AU - Carreón, Tania

AU - Calvert, Geoffrey M.

AU - Davis-King, Karen E.

AU - Schulte, Paul A.

AU - Sanderson, Wayne T.

AU - Ward, Elizabeth M.

AU - Connally, L. Barbara

AU - Heineman, Ellen F.

AU - Mandel, Jack S.

AU - Morton, Roscoe F.

AU - Reding, Douglas J.

AU - Rosenman, Kenneth D.

AU - Talaska, Glenn

PY - 2004/12

Y1 - 2004/12

N2 - The National Institute for Occupational Safety and Health evaluated farm pesticide exposure and glioma risk in a study that included 457 glioma cases and 648 population-based controls, all adult men (18–80 yr old) and nonmetropolitan residents of Iowa, Michigan, Minnesota, and Wisconsin. Multiple logistic regressions were used to control for farm residence, age, age group, education, and exposure to other pesticides. No associations were found between glioma and 12 specific pesticides. We estimated adjusted odds ratios (ORs) and 95% confidence intervals (Cls) and found reduced glioma risk for insecticides (OR = 0.53, Cl = 0.37–0.77), fumigants (OR = 0.57, Cl = 0.34–0.95), and organochlorines (OR = 0.66, Cl = 0.47–0.94). In analyses excluding proxy respondents (47% of cases) most Cls included 1.0. No positive association of farm pesticide exposure and glioma was found. Other farm exposures may explain the excess brain cancer risk seen in previous studies.

AB - The National Institute for Occupational Safety and Health evaluated farm pesticide exposure and glioma risk in a study that included 457 glioma cases and 648 population-based controls, all adult men (18–80 yr old) and nonmetropolitan residents of Iowa, Michigan, Minnesota, and Wisconsin. Multiple logistic regressions were used to control for farm residence, age, age group, education, and exposure to other pesticides. No associations were found between glioma and 12 specific pesticides. We estimated adjusted odds ratios (ORs) and 95% confidence intervals (Cls) and found reduced glioma risk for insecticides (OR = 0.53, Cl = 0.37–0.77), fumigants (OR = 0.57, Cl = 0.34–0.95), and organochlorines (OR = 0.66, Cl = 0.47–0.94). In analyses excluding proxy respondents (47% of cases) most Cls included 1.0. No positive association of farm pesticide exposure and glioma was found. Other farm exposures may explain the excess brain cancer risk seen in previous studies.

KW - Agricultural workers' diseases

KW - Case-control studies

KW - Glioma

KW - Pesticides

KW - Rural population

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SN - 0003-9896

VL - 59

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EP - 657

JO - Archives of Environmental Health

JF - Archives of Environmental Health

IS - 12

ER -

Gliomas and Farm Pesticide Exposure in Men: The Upper Midwest Health Study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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