TY - JOUR
T1 - Global impact
T2 - Elucidating plant responses to viral infection
AU - Whitham, Steven A.
AU - Yang, Chunling
AU - Goodin, Michael M.
PY - 2006/11
Y1 - 2006/11
N2 - Viruses induce a variety of responses in host cells that are mediated by perturbation of different signaling pathways. Advances in our understanding of the functions of viral proteins, plant biology in general, as well as technologies for profiling gene expression have converged in recent years to provide new insight into the events occurring inside susceptible and resistant host cells in response to virus infection. These effects range from nonspecific changes in gene expression due to the general accumulation of viral proteins to those responses that are initiated by the specific interactions between virus and host proteins. Here, we discuss a variety of expression profiling methods and approaches that have been used to study the effects of viruses on host transcriptomes. These studies have identified distinct sets of genes that have altered expression profiles in response to viruses, including stress- and defense-related genes. The activities of viral RNA silencing suppressors and interference with hormone signaling or biogenesis also influence plant gene expression and lead to developmental abnormalities.
AB - Viruses induce a variety of responses in host cells that are mediated by perturbation of different signaling pathways. Advances in our understanding of the functions of viral proteins, plant biology in general, as well as technologies for profiling gene expression have converged in recent years to provide new insight into the events occurring inside susceptible and resistant host cells in response to virus infection. These effects range from nonspecific changes in gene expression due to the general accumulation of viral proteins to those responses that are initiated by the specific interactions between virus and host proteins. Here, we discuss a variety of expression profiling methods and approaches that have been used to study the effects of viruses on host transcriptomes. These studies have identified distinct sets of genes that have altered expression profiles in response to viruses, including stress- and defense-related genes. The activities of viral RNA silencing suppressors and interference with hormone signaling or biogenesis also influence plant gene expression and lead to developmental abnormalities.
KW - Microarray
KW - Plant-virus interactions
UR - http://www.scopus.com/inward/record.url?scp=33750209744&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33750209744&partnerID=8YFLogxK
U2 - 10.1094/MPMI-19-1207
DO - 10.1094/MPMI-19-1207
M3 - Review article
C2 - 17073303
AN - SCOPUS:33750209744
SN - 0894-0282
VL - 19
SP - 1207
EP - 1215
JO - Molecular Plant-Microbe Interactions
JF - Molecular Plant-Microbe Interactions
IS - 11
ER -